TYW1B Antibodies

AND TYW1B ELISA kits, TYW1B Proteins

Many biological assays use antibodies to detect TYW1B, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TYW1B in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TYW1B antibodies...

We validate the specificity of these antibodies to TYW1B by testing them on tissues known to express TYW1B positively and negatively. Browse below to find the TYW1B antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TYW1B Infographic by Boster Bio

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TYW1B Overview

Facts about S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1B.

TYW1B 3D structure. Source: alphafold

S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1B (TYW1B)

Probable component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA.

Catalyzes the condensation of N- methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine, an intermediate in wybutosine biosynthesis (By similarity). .

Gene Information

Human
Gene Name:	TYW1B
Uniprot:	Q6NUM6
Entrez:	441250

Family

Belongs to:

TYW1 family

Alternative Names

LINC00069; Long Intergenic Non-Protein Coding RNA 69; NCRNA00069; Non-Protein Coding RNA 69; Radical S-Adenosyl Methionine And Flavodoxin Domain-Containing Protein 2; radical S-adenosyl methionine and flavodoxin domains 1; RSAFD2; S-Adenosyl-L-Methionine-Dependent TRNA 4-Demethylwyosine Synthase; TRNA Wybutosine-Synthesizing Protein 1 Homolog B ; TRNA-YW Synthesizing Protein 1 Homolog B (Non-Protein Coding); TRNA-YW Synthesizing Protein 1 Homolog B (S. Cerevisiae); TRNA-YW Synthesizing Protein 1 Homolog B

Molecular Weight

Mass (kDA):
76.946 kDA

Genomic Context


Human

Location:	7q11.22-q11.23
Sequence:	7; NC_000007.14 (72574513..72828200, complement)

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TYW1B

References

PMID: 14702039 by Ota T., et al. Complete sequencing and characterization of 21,243 full-length human cDNAs.

PMID: 12853948 by Hillier L.W., et al. The DNA sequence of human chromosome 7.