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- Table of Contents
THRB Antibodies
AND THRB ELISA kits, THRB Proteins
Many biological assays use antibodies to detect THRB, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with THRB in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop THRB antibodies...
Designing an IHC experiment for THRB? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the THRB IHC GuideTHRB Infographic by Boster Bio
All THRB Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA
$480
Cat # EKC1668
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1668
1 kit, containing one 96-well plate and all necessary reagents
Human
$960
Cat # LS007068
20 µg, 100 µg
Cat # LS007068
20 µg, 100 µg
THRB Overview
Facts about Thyroid hormone receptor beta.
Thyroid hormone receptor beta (THRB)
Nuclear hormone receptor which can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | THRB |
| Uniprot: | P10828 |
| Entrez: | 7068 |
Family
| Belongs to: |
|---|
| nuclear hormone receptor family |
Alternative Names
avian erythroblastic leukemia viral (v-erb-a) oncogene homolog 2; c-erbA-2; c-erbA-beta; ERBA2MGC126109; ERBA-BETA; GRTH; MGC126110; NR1A2; NR1A2thyroid hormone receptor, beta (avian erythroblastic leukemia viral (v-erb-a)oncogene homolog 2); Nuclear receptor subfamily 1 group A member 2; oncogene ERBA2; PRTH; THR1pituitary resistance to thyroid hormone; THRB; THRB1; THRB2; thyroid hormone receptor beta 1; thyroid hormone receptor beta; thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a)oncogene homolog 2, avian); TR beta 1; v-ErbA2
Molecular Weight
Mass (kDA):
52.788 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 3p24.2 |
| Sequence: | 3; NC_000003.12 (24117153..24495708, complement) |
Subcellular Localizations
Nucleus.
Diseases
- Malignant Neoplasms
- Neoplasms
- Carcinoma
- Thyroid Hormone Resistance Syndrome
- Hypothyroidism
- Carcinogenesis
- Thyroid Neoplasm
- Malignant Neoplasm Of Thyroid
- Von Hippel-lindau Syndrome
- Pituitary Diseases
- Malignant Squamous Cell Neoplasm
- Hyperplasia
- Neoplasm Metastasis
Interacting Proteins
- Ncor1
Pathways
- Cell Proliferation
- Translation
- Methylation
- Secretion
- Pathogenesis
- Fermentation
- Localization
- Dna Methylation
- Energy Homeostasis
- Brain Development
- Regulation Of Gene Expression
- Cell Cycle
- Cell Growth
PTMs
- Methylation
- Phosphorylation
- Oxidation
Research Areas
- Cancer
- Neuroscience
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/THRB
bosterbio.com/bosterbio-gene-info-cards/THRB
References
PMID: 3034496 by Weinberger C., et al. Human steroid receptors and erbA proto-oncogene products: members of a new superfamily of enhancer binding proteins.
PMID: 2879243 by Weinberger C., et al. The c-erb-A gene encodes a thyroid hormone receptor.