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- Table of Contents
Facts about Toll-like receptor 13.
Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory reaction. Specifically binds the 5'-CGGAAAGACC-3' sequence on bacterial 23S rRNA, a succession also jumped by MLS group antibiotics (including erythromycin).
| Mouse | |
|---|---|
| Gene Name: | Tlr13 |
| Uniprot: | Q6R5N8 |
| Entrez: | 279572 |

| Belongs to: |
|---|
| Toll-like receptor family |

TLR13; TLR-13
Mass (kDA):
114.443 kDA

| Mouse | |
|---|---|
| Location: | X|X D |
| Sequence: | X; |

PMID: 14993594 by Tabeta K., et al. Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection.
PMID: 17452530 by Brinkmann M.M., et al. The interaction between the ER membrane protein UNC93B and TLR3, 7, and 9 is crucial for TLR signaling.