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- Table of Contents
Designing a Western blot for TNFRSF14? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the TNFRSF14 Western Blot Guide
Facts about Tumor necrosis factor receptor superfamily member 14.
Receptor for BTLA.
Receptor for TNFSF14/LIGHT and homotrimeric TNFSF1/lymphotoxin-alpha.Involved in lymphocyte activation. Plays an important role in HSV pathogenesis because it enhanced the entry of numerous wild-type HSV strains of both serotypes to CHO cells, and mediated HSV entry into activated human T-cells.
| Human | |
|---|---|
| Gene Name: | TNFRSF14 |
| Uniprot: | Q92956 |
| Entrez: | 8764 |

| Belongs to: |
|---|
| tumor necrosis factor receptor superfamily |

ATAR; CD270 antigen; CD270; CD40-like protein; Herpes virus entry mediator A; Herpesvirus entry mediator A; HveA; HVEM; HVEMTR2HVEAATAR; LIGHTR; TNFRSF14; tumor necrosis factor receptor superfamily member 14; tumor necrosis factor receptor superfamily, member 14 (herpesvirus entrymediator); Tumor necrosis factor receptor-like 2; tumor necrosis factor receptor-like gene2
Mass (kDA):
30.392 kDA

| Human | |
|---|---|
| Location: | 1p36.32 |
| Sequence: | 1; NC_000001.11 (2556365..2565622) |
Widely expressed, with the highest expression in lung, spleen and thymus.
Cell membrane; Single-pass type I membrane protein.





PMID: 8898196 by Montgomery R.I., et al. Herpes simplex virus-1 entry into cells mediated by a novel member of the TNF/NGF receptor family.
PMID: 9162061 by Kwon B.S., et al. A newly identified member of the tumor necrosis factor receptor superfamily with a wide tissue distribution and involvement in lymphocyte activation.