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- Table of Contents
Designing a Western blot for TNFRSF18? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the TNFRSF18 Western Blot Guide
Facts about Tumor necrosis factor receptor superfamily member 18.
Receptor for TNFSF18.
Appears to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death.Mediated NF-kappa-B activation through the TRAF2/NIK pathway. .
| Human | |
|---|---|
| Gene Name: | TNFRSF18 |
| Uniprot: | Q9Y5U5 |
| Entrez: | 8784 |

| Belongs to: |
|---|
| No superfamily |

Activation-inducible TNFR family receptor; AITR; AITRTNF receptor superfamily activation-inducible protein; CD357 antigen; CD357; GITR; GITR-D; GITRtumor necrosis factor receptor superfamily member 18; Glucocorticoid-induced TNFR-related protein; TNFRSF18; tumor necrosis factor receptor superfamily, member 18
Mass (kDA):
26 kDA

| Human | |
|---|---|
| Location: | 1p36.33 |
| Sequence: | 1; NC_000001.11 (1203508..1207901, complement) |
Expressed in lymph node, peripheral blood leukocytes and weakly in spleen.
[Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Secreted.





PMID: 10074428 by Gurney A.L., et al. Identification of a new member of the tumor necrosis factor family and its receptor, a human ortholog of mouse GITR.
PMID: 10037686 by Kwon B., et al. Identification of a novel activation-inducible protein of the tumor necrosis factor receptor superfamily and its ligand.