Trem3 Antibodies

AND Trem3 ELISA kits, Trem3 Proteins

Many biological assays use antibodies to detect Trem3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Trem3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Trem3 antibodies...

We validate the specificity of these antibodies to Trem3 by testing them on tissues known to express Trem3 positively and negatively. Browse below to find the Trem3 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Trem3 Infographic by Boster Bio

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Trem3 Overview

Facts about Triggering receptor expressed on myeloid cells 3.

Trem3 3D structure. Source: alphafold

Triggering receptor expressed on myeloid cells 3 (Trem3)

Types a receptor signaling complex with TYROBP/DAP12 that mediates activation of macrophages as part of the innate immune response. .

Gene Information

Mouse
Gene Name:	Trem3
Uniprot:	Q9JKE1
Entrez:	58218

Family

Belongs to:

No superfamily

Alternative Names

TREM3; TREM-3

Molecular Weight

Mass (kDA):
20.452 kDA

Genomic Context


Mouse

Location:	17\|17 C
Sequence:	17;

Tissue Specificity

Expressed in macrophages and in T-cells.

Diseases

Systemic Infection
Inflammation
Inflammatory Response
Pneumonia
Infective Disorder
Septic Shock
Bacterial Infections
Severe Sepsis
Pneumonia, Bacterial
Systemic Inflammatory Response Syndrome
Pneumonia, Ventilator-associated
Porphyria Cutanea Tarda
Community-acquired Infections

Pleural Effusion Disorder
Innate Immune Response
Lung Diseases
Dementia
Malignant Neoplasms
Arthritis
Tuberculosis

Pathways

Inflammatory Response
Secretion
Pathogenesis
Immune Response
Phagocytosis
Cytokine Production
Innate Immune Response
Cell Activation
Acute Inflammatory Response
Neutrophil Degranulation
Cell Maturation
Osteoclast Differentiation
Leukocyte Activation

Cell Proliferation
Respiratory Burst
Neutrophil Activation
Macrophage Activation
Bone Resorption
Rna Interference
Cell Adhesion

PTMs

Phosphorylation
Carboxylation

Biotinylation
Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Trem3

References

PMID: 11754004 by Chung D.H., et al. Characterization of TREM-3, an activating receptor on mouse macrophages: definition of a family of single Ig domain receptors on mouse chromosome 17.