Txndc8 Antibodies

AND Txndc8 ELISA kits, Txndc8 Proteins

Many biological assays use antibodies to detect Txndc8, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Txndc8 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Txndc8 antibodies...

We validate the specificity of these antibodies to Txndc8 by testing them on tissues known to express Txndc8 positively and negatively. Browse below to find the Txndc8 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Txndc8 Infographic by Boster Bio

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Txndc8 Overview

Facts about Thioredoxin domain-containing protein 8.

Thioredoxin domain-containing protein 8 (Txndc8)

May be required for post-translational modifications of proteins required for acrosomal biogenesis. May act by reducing disulfide bonds within the sperm (By similarity).

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Gene Information

Mouse
Gene Name:	Txndc8
Uniprot:	Q69AB2
Entrez:	67402

Family

Belongs to:

thioredoxin family

Alternative Names

Thioredoxin domain-containing protein 8

Molecular Weight

Mass (kDA):
14.517 kDA

Genomic Context


Mouse

Location:	4\|4 B3
Sequence:	4;

Tissue Specificity

Testis-specific. Only expressed during spermiogenesis, prominently in the Golgi apparatus of pachytene spermatocytes and round and elongated spermatids, with a transient localization in the developing acrosome of round spermatids (at protein level).

PTMs

Disulfide bond

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Txndc8

References

PMID: 15181017 by Jimenez A., et al. Spermatocyte/spermatid-specific thioredoxin-3, a novel Golgi apparatus-associated thioredoxin, is a specific marker of aberrant spermatogenesis.

PMID: 15781233 by Jimenez A., et al. Absolute mRNA levels and transcriptional regulation of the mouse testis-specific thioredoxins.