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UBE2E3 Antibodies
AND UBE2E3 ELISA kits, UBE2E3 Proteins
Many biological assays use antibodies to detect UBE2E3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with UBE2E3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop UBE2E3 antibodies...
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UBE2E3 Infographic by Boster Bio
All UBE2E3 Products
Product
Figures
Specificity
Applications
Price
Dog, Human, Monkey, Mouse, Rat
Flow Cytometry, IF, IHC, WB
$523
Cat # M09303
100 µl
Cat # M09303
100 µl
UBE2E3 Overview
Facts about Ubiquitin-conjugating enzyme E2 E3.
Ubiquitin-conjugating enzyme E2 E3 (UBE2E3)
Accepts ubiquitin in the E1 complicated and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys- 11'- and 'Lys-48'-, as well as 'Lys-63'-linked polyubiquitination.
Participates in the regulation of transepithelial sodium transport in renal cells. May be involved in cell growth arrest.
Gene Information
| Human | |
|---|---|
| Gene Name: | UBE2E3 |
| Uniprot: | Q969T4 |
| Entrez: | 10477 |
Family
| Belongs to: |
|---|
| ubiquitin-conjugating enzyme family |
Alternative Names
E2-23K; EC 6.3.2.19; UBCE4; UbcH9; UBCH9ubiquitin-conjugating enzyme E2E 3 (homologous to yeast UBC4/5); UbcM2; UBE2E3; Ubiquitin carrier protein E3; ubiquitin-conjugating enzyme E2 E3; Ubiquitin-conjugating enzyme E2-23 kDa; ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast); Ubiquitin-protein ligase E3
Molecular Weight
Mass (kDA):
22.913 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 2q31.3 |
| Sequence: | 2; NC_000002.12 (180980385..181063427) |
Tissue Specificity
Ubiquitously expressed at low levels. Highly expressed in skeletal muscle.
Subcellular Localizations
Nucleus. Cytoplasm. Shuttles between the nucleus and cytoplasm in a IPO11-dependent manner.
Diseases
- Adenocarcinoma
- Autoimmune Diseases
- Hypokinesia
- Rheumatism
- Immunologic Deficiency Syndromes
- Gastric Adenocarcinoma
- Autoimmune Reaction
- Neoplasms
- Sjogren's Syndrome
- Hiv Infections
Interacting Proteins
- MID1
- OTUB1
- RNF115
- RNF185
- RNF2
- RNF25
- RNF5
- TRIM39
Pathways
- Cell Proliferation
- Protein Phosphorylation
- Transport
- Cytokine Production
- Cell Cycle
- Regulation Of Cell Proliferation
- Proteolysis
- Pathogenesis
PTMs
- Ubiquitination
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/UBE2E3
bosterbio.com/bosterbio-gene-info-cards/UBE2E3
References
PMID: 10343118 by Ito K., et al. cDNA cloning, characterization, and chromosome mapping of UBE2E3 (alias UbcH9), encoding an N-terminally extended human ubiquitin- conjugating enzyme.
PMID: 15545318 by Plafker S.M., et al. Ubiquitin charging of human class III ubiquitin-conjugating enzymes triggers their nuclear import.