UBE4A Antibodies

AND UBE4A ELISA kits, UBE4A Proteins

Many biological assays use antibodies to detect UBE4A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with UBE4A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop UBE4A antibodies...

We validate the specificity of these antibodies to UBE4A by testing them on tissues known to express UBE4A positively and negatively. Browse below to find the UBE4A antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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UBE4A Infographic by Boster Bio

All UBE4A Products

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Anti-UBE4A Antibody

4 Q&As

Western Blot analysis of extracts from Jurkat cells, using UBE4A Polyclonal Antibody

Immunohistochemical analysis of paraffin-embedded rat-muscle, antibody was diluted at 1:100

Immunohistochemical analysis of paraffin-embedded mouse-muscle, antibody was diluted at 1:100

Human, Mouse, Rat

ELISA, IF, IHC, WB

$399
Cat # A11871
100μl

UBE4A (NM_004788) Human Recombinant Protein

Coomassie blue staining of purified UBE4A protein

$1062
Cat # PROTQ14139
20 µg

Anti-UBE4A Rabbit Monoclonal Antibody

Western blot analysis of UBE4A expression in 293 cell lysate

All lanes use the Antibody at 1:6K dilution for 1 hour at room temperature

Human

Flow Cytometry, IF, ICC, WB

$370
Cat # M11871
100 μl/vial

UBE4A (NM_004788) Human Over-expression Lysate

Human

$960
Cat # LS009354
20 µg, 100 µg

UBE4A Overview

Facts about Ubiquitin conjugation factor E4 A.

UBE4A 3D structure. Source: alphafold

Ubiquitin conjugation factor E4 A (UBE4A)

Ubiquitin-protein ligase that probably acts as an E3 ligase in conjunction with specific E1 and E2 ligases. May also be the E4 ligase mediating the assembly of polyubiquitin chains on substrates ubiquitinated by another E3 ubiquitin ligase.

Mediates 'Lys-48'-linked polyubiquitination of substrates. .

Gene Information

Human
Gene Name:	UBE4A
Uniprot:	Q14139
Entrez:	9354

Family

Belongs to:

ubiquitin conjugation factor E4 family

Alternative Names

E4MGC133315; KIAA0126ubiquitination factor E4A (homologous to yeast UFD2); ubiquitination factor E4A (UFD2 homolog, yeast); UBOX2; UFD2ubiquitin conjugation factor E4 A

Molecular Weight

Mass (kDA):
122.561 kDA

Genomic Context


Human

Location:	11q23.3
Sequence:	11; NC_000011.10 (118359600..118399211)

Subcellular Localizations

Cytoplasm.

Diseases

Malignant Neoplasms
Ulcer
Neoplasms
Colitis
Neuroblastoma
Ulcerative Colitis
Crohn Disease
Cholangiocarcinoma
Cystadenocarcinoma
Uterine Cervical Neoplasm
Inflammatory Bowel Diseases
Malignant Tumor Of Cervix

Intestinal Diseases
Carcinoma
Cervical Intraepithelial Neoplasia
Malignant Neoplasm Of Ovary
Ovarian Neoplasm
Dysmyelopoietic Syndromes
Precancerous Conditions

Interacting Proteins

MAVS

Pathways

Cell Cycle
Localization

PTMs

Ubiquitination

Acetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/UBE4A

References

PMID: 8590280 by Nagase T., et al. Prediction of the coding sequences of unidentified human genes. IV. The coding sequences of 40 new genes (KIAA0121-KIAA0160) deduced by analysis of cDNA clones from human cell line KG-1.

PMID: 12665801 by Gevaert K., et al. Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides.