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- Table of Contents
Designing an IHC experiment for UBXN1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the UBXN1 IHC Guide
Facts about UBX domain-containing protein 1.
Following viral disease, UBXN1 is induced and recruited into the RLR component MAVS. In turn, interferes with MAVS oligomerization, and disrupts the MAVS/TRAF3/TRAF6 signalosome.
| Human | |
|---|---|
| Gene Name: | UBXN1 |
| Uniprot: | Q04323 |
| Entrez: | 51035 |

| Belongs to: |
|---|
| No superfamily |

2B28; LOC51035; SAKS1UBA/UBX 33.3 kDa protein; SAPK substrate protein 1; UBX domain protein 1; UBX domain-containing protein 1; UBXD10
Mass (kDA):
33.325 kDA

| Human | |
|---|---|
| Location: | 11q12.3 |
| Sequence: | 11; NC_000011.10 (62676498..62679117, complement) |
Cytoplasm.




PMID: 15362974 by McNeill H., et al. A novel UBA and UBX domain protein that binds polyubiquitin and VCP and is a substrate for SAPKs.
PMID: 18775313 by Alexandru G., et al. UBXD7 binds multiple ubiquitin ligases and implicates p97 in HIF1alpha turnover.