Urocortin-2 Antibodies

AND UCN2 ELISA kits, Urocortin-2 Proteins

Many biological assays use antibodies to detect Urocortin-2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Urocortin-2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Urocortin-2 antibodies...

We validate the specificity of these antibodies to Urocortin-2 by testing them on tissues known to express UCN2 positively and negatively. Browse below to find the UCN2 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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UCN2 Infographic by Boster Bio

All UCN2 Products

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Applications

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Anti-Urocortin-2 UCN2 Antibody

Western blot analysis of extracts of rat skin cells, using UCN2 antibody

Immunohistochemistry of paraffin-embedded mouse heart using UCN2 antibody at dilution of 1:100 (40x lens)

Immunofluorescence analysis of U2OS cell using UCN2 antibody

Human, Mouse, Rat

IF, IHC, WB

$405
Cat # A03814
100ul

UCN2 (NM_033199) Human Over-expression Lysate

Human

$628
Cat # LS090226
20 µg, 100 µg

UCN2 Overview

Facts about Urocortin-2.

UCN2 3D structure. Source: alphafold

Urocortin-2 (UCN2)

Suppresses food ingestion, delays gastric emptying and decreases heat-induced edema. Might represent an endogenous ligand for maintaining homeostasis after stress.

Gene Information

Human
Gene Name:	UCN2
Uniprot:	Q96RP3
Entrez:	90226

Family

Belongs to:

sauvagine/corticotropin-releasing factor/urotensin I family

Alternative Names

SRPUrocortin II; Stresscopin-related peptide; Ucn II; UCNI; UCN-II; UR; urocortin 2; urocortin-2; URPUrocortin-related peptide

Molecular Weight

Mass (kDA):
12.146 kDA

Genomic Context


Human

Location:	3p21.31
Sequence:	3; NC_000003.12 (48561718..48563781, complement)

Subcellular Localizations

Secreted.

Diseases

Heart Failure
Inflammation
Nervousness
Heart Diseases
Anxiety Disorders
Hypoxia
Pituitary Diseases
Malignant Neoplasms
Hypertrophy
Polyuria
Reperfusion Injury
Infarction

Inflammatory Response
Cardiovascular Diseases
Myocardial Infarction
Obesity
Carcinoma
Physiological Stress
Myocardial Reperfusion Injury

Pathways

Secretion
Localization
Excretion
Cell Activation
Immune Response
Diuresis
Inflammatory Response
Endocytosis
Natriuresis
Gastric Emptying
Pathogenesis
Gene Silencing
Catecholamine Secretion

Sensitization
Reverse Transcription
Translation
Lipid Homeostasis
Feeding Behavior
Estrus
Hormone Secretion

PTMs

Phosphorylation

Acylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/UCN2

References

PMID: 11329063 by Hsu S.Y., et al. Human stresscopin and stresscopin-related peptide are selective ligands for the type 2 corticotropin-releasing hormone receptor.

PMID: 23493376 by Vaughan J.M., et al. Posttranslational processing of human and mouse urocortin 2: characterization and bioactivity of gene products.