UCP2 Antibodies

AND UCP2 ELISA kits, UCP2 Proteins

Many biological assays use antibodies to detect UCP2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with UCP2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop UCP2 antibodies...

We validate the specificity of these antibodies to UCP2 by testing them on tissues known to express UCP2 positively and negatively. Browse below to find the UCP2 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for UCP2? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the UCP2 Western Blot Guide

UCP2 Infographic by Boster Bio

All UCP2 Products

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Anti-UCP2 Antibody Picoband®

Western blot analysis of UCP2 using anti-UCP2 antibody (A02256-1)

Human, Mouse, Rat

$370
Cat # A02256-1
100 μg/vial

UCP2 Overview

Facts about Mitochondrial uncoupling protein 2.

UCP2 3D structure. Source: alphafold

Mitochondrial uncoupling protein 2 (UCP2)

UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation from ATP synthesis. Because of this, energy is dissipated in the kind of heat.

Gene Information

Human
Gene Name:	UCP2
Uniprot:	P55851
Entrez:	7351

Family

Belongs to:

mitochondrial carrier (TC 2.A.29) family

Alternative Names

mitochondrial uncoupling protein 2; SLC25A8; SLC25A8BMIQ4; Solute carrier family 25 member 8; UCP 2; UCP2; UCPH; uncoupling protein 2 (mitochondrial, proton carrier)

Molecular Weight

Mass (kDA):
33.229 kDA

Genomic Context


Human

Location:	11q13.4
Sequence:	11; NC_000011.10 (73974671..73982872, complement)

Tissue Specificity

Widely expressed in adult human tissues, including tissues rich in macrophages. Most expressed in white adipose tissue and skeletal muscle.

Subcellular Localizations

Mitochondrion inner membrane; Multi-pass membrane protein.

Diseases

Obesity
Diabetes Mellitus
Diabetes Mellitus, Non-insulin-dependent
Insulin Resistance
Malignant Neoplasms
Inflammation
Insulin Sensitivity
Fatty Liver
Nervousness
Hyperglycemia
Neoplasms
Steatohepatitis

Ischemia
Steatosis
Hyperinsulinism
Atherosclerosis
Liver Diseases
Metabolic Diseases
Cardiovascular Diseases

Interacting Proteins

KRTAP10-7

Pathways

Secretion
Insulin Secretion
Transport
Oxidative Phosphorylation
Fatty Acid Oxidation
Pathogenesis
Energy Homeostasis
Cell Death
Aging
Electron Transport
Proton Transport
Localization
Glucose Homeostasis

Neuroprotection
Lipid Oxidation
Cell Proliferation
Response To Cold
Translation
Glycolysis
Electron Transport Chain

PTMs

Oxidation
Phosphorylation
Cleavage
Reduction
Glutathionylation
Methylation

Sumoylation
Acetylation
Carboxylation
Hydroxylation
Deacetylation
Glycosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/UCP2

References

PMID: 9180264 by Boss O., et al. Uncoupling protein-3: a new member of the mitochondrial carrier family with tissue-specific expression.

PMID: 9054939 by Fleury C., et al. Uncoupling protein-2: a novel gene linked to obesity and hyperinsulinemia.

1 Publications of Boster UCP2 Antibodies & ELISA Kits

PubMed ID: 23365696, Exhaustive Training Increases Uncoupling Protein 2 Expression and Decreases Bcl-...

*More publications can be found for each product on its corresponding product page