UGT1A8 Antibodies

AND UGT1A8 ELISA kits, UGT1A8 Proteins

Many biological assays use antibodies to detect UGT1A8, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with UGT1A8 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop UGT1A8 antibodies...

We validate the specificity of these antibodies to UGT1A8 by testing them on tissues known to express UGT1A8 positively and negatively. Browse below to find the UGT1A8 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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UGT1A8 Infographic by Boster Bio

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UGT1A8 (NM_019076) Human Over-expression Lysate

Human

$960
Cat # LS054576
20 µg, 100 µg

UGT1A8 Overview

Facts about UDP-glucuronosyltransferase 1-8.

UGT1A8 3D structure. Source: alphafold

UDP-glucuronosyltransferase 1-8 (UGT1A8)

UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. Isoform 2 lacks transferase activity but acts as a negative regulator of isoform 1.

Gene Information

Human
Gene Name:	UGT1A8
Uniprot:	Q9HAW9
Entrez:	54576

Family

Belongs to:

UDP-glycosyltransferase family

Alternative Names

UDP-glucuronosyltransferase 1-8

Molecular Weight

Mass (kDA):
59.742 kDA

Genomic Context


Human

Location:	2q37.1
Sequence:	2; NC_000002.12 (233617645..233773299)

Tissue Specificity

Colon specific. Isoform 1 and 2 are expressed in liver, kidney, colon and small intestine; isoform 2 but not isoform 1 is expressed in liver (PubMed:18004212).

Subcellular Localizations

Microsome. Endoplasmic reticulum membrane; Single-pass membrane protein.

PTMs

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/UGT1A8

References

PMID: 9535849 by Strassburg C.P., et al. Expression of the UDP-glucuronosyltransferase 1A locus in human colon. Identification and characterization of the novel extrahepatic UGT1A8.

PMID: 11434514 by Gong Q.H., et al. Thirteen UDP-glucuronosyltransferase genes are encoded at the human UGT1 gene complex locus.