Uimc1 Antibodies

AND Uimc1 ELISA kits, Uimc1 Proteins

Many biological assays use antibodies to detect Uimc1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Uimc1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Uimc1 antibodies...

We validate the specificity of these antibodies to Uimc1 by testing them on tissues known to express Uimc1 positively and negatively. Browse below to find the Uimc1 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Uimc1 Infographic by Boster Bio

All Uimc1 Products

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Anti-RAP80 Monoclonal Antibody

1 Q&As

Western blot analysis of RAP80 expression in 293T cell lysate

Human

IF, IHC, ICC, WB

$370
Cat # M06262
100 μl

Anti-RAP80 UIMC1 Antibody

Western blot analysis of RAP80 in 293 cell lysate in (A) the absence and (B) presence of blocking peptide with RAP80 antibody at 2 μg/mL

Immunohistochemistry of RAP80 in human spleen tissue with RAP80 antibody at 2

Immunofluorescence of RAP80 in Human Spleen cells with RAP80 antibody at 20 μg/mL

Human, Mouse

ELISA, IF, IHC-P, WB

$481
Cat # A06262
0.1 mg

Anti-BRCA1-A complex subunit RAP80 UIMC1 Antibody

Western blot analysis of extracts of various cell lines, using UIMC1 antibody at 1:1000 dilution

Immunofluorescence analysis of GFP-RNF168 transgenic U2OS cells using UIMC1 antibody

Human, Mouse, Rat

IF, ICC, WB

$405
Cat # A06262-1
100ul

Anti-UIMC1 Antibody (C-term)

Western blot analysis of lysate from HT-1080 cell line, using UIMC1 Antibody (C-term)

Flow cytometric analysis of MCF-7 cells using UIMC1 Antibody (C-term)(green, ) compared to an isotype control of rabbit IgG(blue)

Human

Flow Cytometry, WB

$299
Cat # A06262-2
80 µl

RAP80 (UIMC1) (NM_016290) Human Over-expression Lysate

Human

$628
Cat # LS051720
20 µg, 100 µg

Uimc1 Overview

Facts about BRCA1-A complex subunit RAP80.

BRCA1-A complex subunit RAP80 (Uimc1)

Ubiquitin-binding protein. Specifically recognizes and binds 'Lys-63'-linked ubiquitin (PubMed:19536136).

Plays a central role in the BRCA1-A complex by specifically binding'Lys-63'- linked ubiquitinated histones H2A and H2AX in DNA lesions sites, leading to goal the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). The BRCA1-A complex also possesses deubiquitinase activity that specifically removes'Lys- 63'-linked ubiquitin on histones H2A and H2AX.

Gene Information

Mouse
Gene Name:	Uimc1
Uniprot:	Q5U5Q9
Entrez:	20184

Family

Belongs to:

RAP80 family

Alternative Names

BRCA1-A complex subunit RAP80; RAP80; RAP80X2HRIP110; receptor associated protein 80; Receptor-associated protein 80; retinoid x receptor interacting protein; Retinoid X receptor-interacting protein 110; RXRIP110; ubiquitin interaction motif containing 1; Ubiquitin interaction motif-containing protein 1; UIMC1; X2HRIP110