UL16-binding protein 2 Antibodies

AND ULBP2 ELISA kits, UL16-binding protein 2 Proteins

Many biological assays use antibodies to detect UL16-binding protein 2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with UL16-binding protein 2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop UL16-binding protein 2 antibodies...

We validate the specificity of these antibodies to UL16-binding protein 2 by testing them on tissues known to express ULBP2 positively and negatively. Browse below to find the ULBP2 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: Septin9 Next: DNAJC5

ULBP2 Infographic by Boster Bio

All ULBP2 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Human ULBP2 ELISA Kit PicoKine®

12 Q&As

Human

ELISA

$499
Cat # EK1593
96 wells/kit, with removable strips.

Anti-N2DL2 ULBP2 Antibody

Human

ELISA, WB

$380
Cat # A03657
100ul

Human ULBP-2 Recombinant Protein

SDS-PAGE

$250
Cat # PROTQ9BZM5
Starting from 10ug

ULBP2 (NM_025217) Human Over-expression Lysate

Human

$628
Cat # LS080328
20 µg, 100 µg

Anti-ULBP2 Antibody

Human

ELISA, IHC, WB

$370
Cat # A03657-1
100 μl/vial

ULBP2 Overview

Facts about UL16-binding protein 2.

ULBP2 3D structure. Source: alphafold

UL16-binding protein 2 (ULBP2)

Binds and activates the KLRK1/NKG2D receptor, mediating natural killer cell cytotoxicity. .

Gene Information

Human
Gene Name:	ULBP2
Uniprot:	Q9BZM5
Entrez:	80328

Family

Belongs to:

MHC class I family

Alternative Names

ALCAN-alpha; N2DL2; N2DL-2; NKG2D ligand 2; NKG2DL2; RAET1H; RAET1HNKG2DL2; retinoic acid early transcript 1 H; Retinoic acid early transcript 1H; UL16 binding protein 2; UL16-binding protein 2; ULBP2; ULBP-2

Molecular Weight

Mass (kDA):
27.368 kDA

Genomic Context


Human

Location:	6q25.1
Sequence:	6; NC_000006.12 (149941947..149949235)

Tissue Specificity

Expressed in various types of cancer cell lines and in the fetus, but not in normal tissues.

Subcellular Localizations

Cell membrane; Lipid-anchor, GPI-anchor. Endoplasmic reticulum. Secreted. In CMV-infected fibroblasts, detected in the endoplasmic reticulum/cis-Golgi.

Diseases

Neoplasms
Malignant Neoplasms
Carcinoma
Leukemia
Cytomegalovirus Infections
Malignant Paraganglionic Neoplasm
Melanoma
Tumor Escape
Neoplasm Metastasis
Myeloid Leukemia
Ovarian Neoplasm
Leukemia, Myelocytic, Acute

Infective Disorder
Lymphoma
Lung Neoplasms
Hiv Infections
Immunologic Deficiency Syndromes
Liver Carcinoma
Liver Diseases

Interacting Proteins

KLRK1

Pathways

Immune Response
Cytolysis
Cell Activation
Cell Recognition
Secretion
Cell Proliferation
Transport
Cell Cycle
Innate Immune Response
Exocytosis
Cell Killing
Senescence
Methylation

Cell Death
Cell Growth
Rna Interference
Lymphocyte Activation
Cell Adhesion
Gene Silencing
Chemokine Production

PTMs

Cleavage
Phosphorylation
Methylation

Demethylation
Glycosylation
Gpi Anchoring

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ULBP2

References

PMID: 11239445 by Cosman D., et al. ULBPs, novel MHC class I-related molecules, bind to CMV glycoprotein UL16 and stimulate NK cytotoxicity through the NKG2D receptor.

PMID: 11444831 by Onda H., et al. A novel secreted tumor antigen with a glycosylphosphatidylinositol- anchored structure ubiquitously expressed in human cancers.