Netrin receptor UNC5D Antibodies

AND UNC5D ELISA kits, Netrin receptor UNC5D Proteins

Many biological assays use antibodies to detect Netrin receptor UNC5D, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Netrin receptor UNC5D in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Netrin receptor UNC5D antibodies...

We validate the specificity of these antibodies to Netrin receptor UNC5D by testing them on tissues known to express UNC5D positively and negatively. Browse below to find the UNC5D antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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UNC5D Infographic by Boster Bio

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Anti-Netrin receptor UNC5D UNC5D Antibody

Human, Mouse

ELISA, WB

$380
Cat # A09136
100ul

UNC5D Overview

Facts about Netrin receptor UNC5D.

UNC5D 3D structure. Source: alphafold

Netrin receptor UNC5D (UNC5D)

Receptor for the netrin NTN4 that promotes neuronal cell survival (By similarity). Plays a role in cell-cell adhesion and cell guidance.

Receptor for netrin involved in cell migration. Plays a role in axon guidance by mediating axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding (By similarity).

Gene Information

Human
Gene Name:	UNC5D
Uniprot:	Q6UXZ4
Entrez:	137970

Family

Belongs to:

unc-5 family

Alternative Names

FLJ16019; KIAA1777Unc5h4; netrin receptor UNC5D; netrin receptor Unc5h4; PRO34692; Protein unc-5 homolog 4; Protein unc-5 homolog D; unc-5 homolog 4; unc-5 homolog D (C. elegans); UNC5D; UNC5H4

Molecular Weight

Mass (kDA):
105.88 kDA

Genomic Context


Human

Location:	8p12
Sequence:	8; NC_000008.11 (35235475..35796550)

Subcellular Localizations

Cell membrane; Single-pass type I membrane protein.

Diseases

Malignant Neoplasms
Nervousness
Colorectal Cancer
Neoplasms
Inflammation
Reperfusion Injury
Colonic Neoplasms
Malignant Tumor Of Colon
Malignant Neoplasm Of Urinary Bladder
Carcinoma
Carcinogenesis
Myopathy

Injury To Kidney
Tumor Angiogenesis
Recurrence (disease Attribute)
Neoplasms, Multiple Primary
Pathologic Neovascularization
Bladder Neoplasm
Cell Invasion

Pathways

Cell Migration
Axon Guidance
Cell Adhesion
Cell Proliferation
Chemokine Production
Tricarboxylic Acid Cycle
Neurogenesis
Oxidative Phosphorylation
Cytokine Production
Neuron Migration
System Development

Cell Death
Nervous System Development
Angiogenesis
Wound Healing
Epithelial Cell Proliferation

PTMs

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/UNC5D

References

PMID: 24691657 by Wang H., et al. Unc5D regulates p53-dependent apoptosis in neuroblastoma cells.

PMID: 24519068 by Wang H., et al. Overexpression of the dependence receptor UNC5H4 inhibits cell migration and invasion, and triggers apoptosis in neuroblastoma cell.