UNKL Antibodies

AND UNKL ELISA kits, UNKL Proteins

Many biological assays use antibodies to detect UNKL, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with UNKL in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop UNKL antibodies...

We validate the specificity of these antibodies to UNKL by testing them on tissues known to express UNKL positively and negatively. Browse below to find the UNKL antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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UNKL Infographic by Boster Bio

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RING finger protein unkempt like (UNKL) (NM_023076) Human Recombinant Protein

Coomassie blue staining of purified UNKL protein

$1249
Cat # PROTQ9H9P5
20 µg

UNKL Overview

Facts about Putative E3 ubiquitin-protein ligase UNKL.

UNKL 3D structure. Source: alphafold

Putative E3 ubiquitin-protein ligase UNKL (UNKL)

May participate in a protein complex showing an E3 ligase activity regulated by RAC1. Ubiquitination is directed towards itself and other substrates, such as SMARCD2/BAF60b.

Intrinsic E3 ligase activity has not yet been proven. .

Gene Information

Human
Gene Name:	UNKL
Uniprot:	Q9H9P5
Entrez:	64718

Family

Belongs to:

unkempt family

Alternative Names

C16orf28; chromosome 16 open reading frame 28; EC 6.3.2.-; FLJ12623; KIAA0734; Putative E3 ubiquitin-protein ligase UNKL; RING finger protein unkempt-like; unkempt homolog (Drosophila)-like; unkempt-like; ZC3H5LMGC5179; ZC3HDC5LFLJ23360

Molecular Weight

Mass (kDA):
73.828 kDA

Genomic Context


Human

Location:	16p13.3
Sequence:	16; NC_000016.10 (1363205..1414749, complement)

Subcellular Localizations

[Isoform 4]: Cytoplasm. Nucleus. Isoform 4 is primarily localized in the cytoplasm but has the ability to shuttle between the nucleus and the cytoplasm.

Interacting Proteins

RAC1
SMARCD2

PTMs

Ubl conjugation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/UNKL

References

PMID: 20148946 by Lores P., et al. The SWI/SNF protein BAF60b is ubiquitinated through a signalling process involving Rac GTPase and the RING finger protein Unkempt.