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UQCRH Antibodies
AND UQCRH ELISA kits, UQCRH Proteins
Many biological assays use antibodies to detect UQCRH, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with UQCRH in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop UQCRH antibodies...
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UQCRH Infographic by Boster Bio
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UQCRH Overview
Facts about Cytochrome b-c1 complex subunit 6, mitochondrial.
Cytochrome b-c1 complex subunit 6, mitochondrial (UQCRH)
This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1.
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Gene Information
| Human | |
|---|---|
| Gene Name: | UQCRH |
| Uniprot: | P07919 |
| Entrez: | 7388 |
Family
| Belongs to: |
|---|
| UQCRH/QCR6 family |
Alternative Names
Complex III subunit 6; Complex III subunit VIII; cytochrome b-c1 complex subunit 6, mitochondrial; Cytochrome c1 non-heme 11 kDa protein; MGC111572; Mitochondrial hinge protein; QCR6; Ubiquinol-cytochrome c reductase complex 11 kDa protein; ubiquinol-cytochrome c reductase hinge protein; ubiquinol-cytochrome c reductase, complex III subunit VIII; UQCR8
Molecular Weight
Mass (kDA):
10.739 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1p33 |
| Sequence: | 1; NC_000001.11 (46303698..46316776) |
Subcellular Localizations
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
Diseases
- Malignant Neoplasms
- Malignant Neoplasm Of Breast
- Neoplasms
- Mammary Neoplasms
- Cell Invasion
- Cell Transformation, Neoplastic
- Leukemia, T-cell
- Myeloid Leukemia, Chronic
- Diabetes Mellitus
- Ewings Sarcoma-primitive Neuroectodermal Tumor (pnet)
- Sarcoma
- Endoplasmic Reticulum Stress
Interacting Proteins
- ARL8A
- RNF24
Pathways
- Oxidative Phosphorylation
- Methylation
- Release Of Cytochrome C From Mitochondria
- Insulin Secretion
- Aging
- Glycolysis
- Apoptotic Process
PTMs
- Demethylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/UQCRH
bosterbio.com/bosterbio-gene-info-cards/UQCRH
References
PMID: 2826252 by Ohta S., et al. An extremely acidic amino-terminal presequence of the precursor for the human mitochondrial hinge protein.
PMID: 7684318 by Liu A.Y., et al. Elevated expression of the human mitochondrial hinge protein gene in cancer.