URGCP Antibodies

AND URGCP ELISA kits, URGCP Proteins

Many biological assays use antibodies to detect URGCP, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with URGCP in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop URGCP antibodies...

We validate the specificity of these antibodies to URGCP by testing them on tissues known to express URGCP positively and negatively. Browse below to find the URGCP antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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URGCP Infographic by Boster Bio

All URGCP Products

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Specificity

Applications

Price

URG4 (URGCP) (NM_001077663) Human Over-expression Lysate

Human

$960
Cat # LS055665
20 µg, 100 µg

Anti-URG4/URGCP Antibody

Human

ELISA, IP, IF, IHC, ICC, WB

$370
Cat # A07681-1
100 μl/vial

URGCP Overview

Facts about Up-regulator of cell proliferation.

URGCP 3D structure. Source: alphafold

Up-regulator of cell proliferation (URGCP)

May be involved in cell cycle progression through the regulation of cyclin D1 expression. May participate in the development of hepatocellular carcinoma (HCC) by promoting hepatocellular growth and survival.

May play an important role in development of gastric cancer. .

Gene Information

Human
Gene Name:	URGCP
Uniprot:	Q8TCY9
Entrez:	55665

Family

Belongs to:

TRAFAC class dynamin-like GTPase superfamily

Alternative Names

DKFZp686O0457; FLJ20654; HBV X protein up-regulated gene 4 protein; HBxAg up-regulated gene 4 protein; KIAA1507; up-regulated gene 4; upregulator of cell proliferation; URG4DKFZp666G166

Molecular Weight

Mass (kDA):
104.987 kDA

Genomic Context


Human

Location:	7p13
Sequence:	7; NC_000007.14 (43875894..43926411, complement)

Tissue Specificity

Strongly expressed in hepatitis B virus- infected liver and in HCC cells. Also highly expressed in well- differentiated gastric cancer tissues and various gastric cancer cell lines.

Subcellular Localizations

Cytoplasm. Nucleus. In epithelial cells localized predominantly in the cytoplasm and occasionally in nuclei.

Diseases

Malignant Neoplasms
Liver Carcinoma
Hepatocarcinogenesis
Carcinoma
Cell Invasion
Malignant Neoplasm Of Prostate
Cell Transformation, Neoplastic
Neoplasms

Malignant Paraganglionic Neoplasm
Hepatitis B
Carcinogenesis

Pathways

Cell Proliferation
Cell Cycle
Rna Interference

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/URGCP

References

PMID: 12082552 by Tufan N.L.S., et al. Hepatitis Bx antigen stimulates expression of a novel cellular gene, URG4, that promotes hepatocellular growth and survival.

PMID: 17217616 by Song J., et al. Enhanced cell survival of gastric cancer cells by a novel gene URG4.