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- Table of Contents
Facts about Ubiquitin carboxyl-terminal hydrolase 48.
May be involved in the regulation of NF-kappa-B activation by TNF receptor superfamily via its interactions with RELA and TRAF2. May also play a regulatory role at postsynaptic sites.
Human | |
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Gene Name: | USP48 |
Uniprot: | Q86UV5 |
Entrez: | 84196 |
Belongs to: |
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peptidase C19 family |
Deubiquitinating enzyme 48; DKFZp762M1713; EC 3.1.2.15; EC 3.4.19.12; FLJ11328; FLJ20103; FLJ23054; FLJ23277; MGC132556; MGC14879; RAP1GA1; synUSP; ubiquitin carboxyl-terminal hydrolase 48; ubiquitin specific peptidase 48; ubiquitin specific protease 31; ubiquitin specific protease 48; ubiquitin thioesterase 48; Ubiquitin thiolesterase 48; Ubiquitin-specific-processing protease 48; USP31; USP48
Mass (kDA):
119.032 kDA
Human | |
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Location: | 1p36.12 |
Sequence: | 1; NC_000001.11 (21678298..21784146, complement) |
Widely expressed.
Cytoplasm. Nucleus.
PMID: 15354349 by Lockhart P.J., et al. Identification of the human ubiquitin specific protease 31 (USP31) gene: structure, sequence and expression analysis.
PMID: 14715245 by Quesada V., et al. Cloning and enzymatic analysis of 22 novel human ubiquitin-specific proteases.