USP9Y Antibodies

AND USP9Y ELISA kits, USP9Y Proteins

Many biological assays use antibodies to detect USP9Y, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with USP9Y in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop USP9Y antibodies...

We validate the specificity of these antibodies to USP9Y by testing them on tissues known to express USP9Y positively and negatively. Browse below to find the USP9Y antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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USP9Y Infographic by Boster Bio

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USP9Y Overview

Facts about Probable ubiquitin carboxyl-terminal hydrolase FAF-Y.

USP9Y 3D structure. Source: alphafold

Probable ubiquitin carboxyl-terminal hydrolase FAF-Y (USP9Y)

May function as a ubiquitin-protein or polyubiquitin hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. May thus play an important regulatory role at the level of protein turnover by preventing degradation of proteins through the removal of conjugated ubiquitin.

Essential part of TGF-beta/BMP signaling cascade. Deubiquitinates monoubiquitinated SMAD4, opposing the activity of E3 ubiquitin-protein ligase TRIM33.

Gene Information

Human
Gene Name:	USP9Y
Uniprot:	O00507
Entrez:	8287

Family

Belongs to:

peptidase C19 family

Alternative Names

Deubiquitinating enzyme FAF-Y; DFFRYFLJ33043; EC 3.1.2.15; EC 3.4.19.12; Fat facets protein-related, Y-linked; probable ubiquitin carboxyl-terminal hydrolase FAF-Y; ubiquitin specific peptidase 9, Y-linked (fat facets-like, Drosophila); ubiquitin specific peptidase 9, Y-linked; ubiquitin thioesterase FAF-Y; Ubiquitin thiolesterase FAF-Y; ubiquitin-specific processing protease FAF-Y; Ubiquitin-specific protease 9, Y chromosome; Ubiquitin-specific-processing protease FAF-Y

Molecular Weight

Mass (kDA):
291.077 kDA

Genomic Context


Human

Location:	Yq11.221
Sequence:	Y; NC_000024.10 (12701231..12860839)

Tissue Specificity

Widely expressed in embryonic and adult tissues.

Subcellular Localizations

Cytoplasm.

Diseases

Azoospermia
Infertility
Oligospermia
Male Infertility
Congenital Absence Of Germinal Epithelium Of Testes
Malignant Neoplasms
Partial Deletion Of Y
Neoplasms
Sex Chromosome Aberrations
Cytogenetic Abnormality
De Novo Mutation
Dwarfism
Malignant Paraganglionic Neoplasm

Prostatic Neoplasms
Malignant Neoplasm Of Prostate
Coronary Heart Disease
Malignant Neoplasm Of Breast
Del(1p36)
Benign Prostatic Hypertrophy
Meningeal Neoplasms

Pathways

Spermatogenesis
Brain Development
Sex Determination
Localization
Embryo Development
Cell Development
Fertilization
Dna Repair
Germ Cell Development
Translation
Cell Cycle
Prophase

Mitotic Cell Cycle
Interphase
Pachytene
Pathogenesis
Rna Interference
Oncogenesis

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/USP9Y

References

PMID: 8922996 by Jones M.H., et al. The Drosophila developmental gene fat facets has a human homologue in Xp11.4 which escapes X-inactivation and has related sequences on Yq11.2.

PMID: 9381176 by Lahn B.T., et al. Functional coherence of the human Y chromosome.