USP47 Antibodies

AND USP47 ELISA kits, USP47 Proteins

Many biological assays use antibodies to detect USP47, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with USP47 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop USP47 antibodies...

We validate the specificity of these antibodies to USP47 by testing them on tissues known to express USP47 positively and negatively. Browse below to find the USP47 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for USP47? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the USP47 IHC Guide

USP47 Infographic by Boster Bio

All USP47 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-USP47 Antibody (Center)

Human

IHC-P, WB

$299
Cat # M07648
80 µl

USP47 (NM_017944) Human Over-expression Lysate

Human

$960
Cat # LS055031
20 µg, 100 µg

USP47 Overview

Facts about Ubiquitin carboxyl-terminal hydrolase 47.

USP47 3D structure. Source: alphafold

Ubiquitin carboxyl-terminal hydrolase 47 (USP47)

Ubiquitin-specific protease that specifically deubiquitinates monoubiquitinated DNA polymerase beta (POLB), stabilizing POLB thereby playing a role in base-excision repair (BER). Acts as a regulator of cell growth and genome integrity.

May also indirectly regulate CDC25A expression at a transcriptional level. .

Gene Information

Human
Gene Name:	USP47
Uniprot:	Q96K76
Entrez:	55031

Family

Belongs to:

peptidase C19 family

Alternative Names

Deubiquitinating enzyme 47; DKFZp686C13257; EC 3.4.19.12; FLJ20727; Trf (TATA binding protein-related factor)-proximal homolog (Drosophila); Trf (TATA binding protein-related factor)-proximal homolog; TRFP; ubiquitin carboxyl-terminal hydrolase 47; ubiquitin specific peptidase 47; ubiquitin specific protease 47; ubiquitin thioesterase 47; Ubiquitin thiolesterase 47; Ubiquitin-specific-processing protease 47; USP47

Molecular Weight

Mass (kDA):
157.311 kDA

Genomic Context


Human

Location:	11p15.3
Sequence:	11; NC_000011.10 (11841972..11961887)

Tissue Specificity

Expressed in skeletal muscle, heart and testis.

Subcellular Localizations

Cytoplasm.

Diseases

Malignant Neoplasms
Hereditary Malignant Neoplasm
Neoplasm Metastasis
Nerve Degeneration
Premature Aging Syndrome
Tissue Adhesions

Interacting Proteins

AP4M1

Pathways

Cell Motility
Dna Damage Checkpoint
Aging
Dna Repair
Cellular Process
Cell Growth

Cell-cell Adhesion

PTMs

Acetylation

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/USP47

References

PMID: 14715245 by Quesada V., et al. Cloning and enzymatic analysis of 22 novel human ubiquitin-specific proteases.

PMID: 19966869 by Peschiaroli A., et al. The ubiquitin-specific protease USP47 is a novel beta-TRCP interactor regulating cell survival.