VIPAS39 Antibodies

AND VIPAS39 ELISA kits, VIPAS39 Proteins

Many biological assays use antibodies to detect VIPAS39, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with VIPAS39 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop VIPAS39 antibodies...

We validate the specificity of these antibodies to VIPAS39 by testing them on tissues known to express VIPAS39 positively and negatively. Browse below to find the VIPAS39 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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VIPAS39 Infographic by Boster Bio

All VIPAS39 Products

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Anti-VIPAS39 Antibody

Western blot analysis of extracts of various cell lines, using VIPAS39 antibody at 1:1000 dilution

Human, Mouse

$405
Cat # A07696
100ul

VIPAS39 Overview

Facts about Spermatogenesis-defective protein 39 homolog.

VIPAS39 3D structure. Source: alphafold

Spermatogenesis-defective protein 39 homolog (VIPAS39)

Proposed to be involved in endosomal maturation implicating in part VPS33B. In epithelial cells, the VPS33B:VIPAS39 complex may play a role in the apical RAB11A- dependent recycling pathway and in the maintenance of the apical- basolateral polarity (PubMed:20190753).

May play a role in lysosomal trafficking, probably via association with the core HOPS complex at a different population of endosomes; the acts seems to be indepenedent of VPS33B (PubMed:19109425). May play a role in vesicular trafficking through spermatogenesis (By similarity).

Gene Information

Human
Gene Name:	VIPAS39
Uniprot:	Q9H9C1
Entrez:	63894

Family

Belongs to:

SPE39 family

Alternative Names

C14orf133FLJ12707; hSPE-39; Protein spe-39 homolog; SPE-39; SPE39chromosome 14 open reading frame 133; VPS16B; VPS33B interacting protein, apical-basolateral polarity regulator; VPS33B-interacting protein involved in polarity and apical protein restriction; VPS33B-interacting protein

Molecular Weight

Mass (kDA):
57.005 kDA

Genomic Context


Human

Location:	14q24.3
Sequence:	14; NC_000014.9 (77426675..77457727, complement)

Subcellular Localizations

Cytoplasm. Cytoplasmic vesicle. Early endosome. Recycling endosome. Late endosome. Colocalizes in clusters with VPS33B at cytoplasmic organelles (PubMed:19109425).

Interacting Proteins

Vps11
Vps16
Vps18
VPS33B
VPS41

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/VIPAS39

References

PMID: 19109425 by Zhu G.D., et al. SPE-39 family proteins interact with the HOPS complex and function in lysosomal delivery.

PMID: 20190753 by Cullinane A.R., et al. Mutations in VIPAR cause an arthrogryposis, renal dysfunction and cholestasis syndrome phenotype with defects in epithelial polarization.