Spermatogenesis-defective protein 39 homolog (VIPAS39)

Proposed to be involved in endosomal maturation implicating in part VPS33B. In epithelial cells, the VPS33B:VIPAS39 complex may play a role in the apical RAB11A- dependent recycling pathway and in the maintenance of the apical- basolateral polarity (PubMed:20190753).

May play a role in lysosomal trafficking, probably via association with the core HOPS complex at a different population of endosomes; the acts seems to be indepenedent of VPS33B (PubMed:19109425). May play a role in vesicular trafficking through spermatogenesis (By similarity).