VLDLR Antibodies

AND VLDLR ELISA kits, VLDLR Proteins

Many biological assays use antibodies to detect VLDLR, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with VLDLR in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop VLDLR antibodies...

We validate the specificity of these antibodies to VLDLR by testing them on tissues known to express VLDLR positively and negatively. Browse below to find the VLDLR antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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VLDLR Infographic by Boster Bio

All VLDLR Products

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Product

Figures

Specificity

Applications

Price

Anti-VLDLR Antibody

Human, Mouse, Rat

ELISA, WB

$380
Cat # A02195
100ul

Anti-VLDL Receptor/VLDLR Antibody Picoband®

Western blot analysis of VLDL Receptor/VLDLR using anti-VLDL Receptor/VLDLR antibody (A02195-1)

Flow Cytometry analysis of JK cells using anti-VLDL Receptor/VLDLR antibody (A02195-1)

Human, Mouse, Rat

ELISA, Flow Cytometry, WB

$370
Cat # A02195-1
100 μg/vial

VLDL Receptor (VLDLR) (NM_003383) Human Over-expression Lysate

Human

$960
Cat # LS007436
20 µg, 100 µg

Anti-VLDLR Antibody

Human, Mouse, Rat

ELISA, WB

$370
Cat # A02195-2
100 μl/vial

VLDLR Overview

Facts about Very low-density lipoprotein receptor.

VLDLR 3D structure. Source: alphafold

Very low-density lipoprotein receptor (VLDLR)

Binds VLDL and transports it into cells by endocytosis. So as to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits.

Binding to Reelin induces tyrosine phosphorylation of Dab1 and modulation of Tau phosphorylation (By similarity). .

Gene Information

Human
Gene Name:	VLDLR
Uniprot:	P98155
Entrez:	7436

Family

Belongs to:

No superfamily

Alternative Names

CARMQ1; CHRMQ1; FLJ35024; very low density lipoprotein receptor; very low-density lipoprotein receptor; VLDL R; VLDL receptor; VLDLR; VLDL-R; VLDLRCH

Molecular Weight

Mass (kDA):
96.098 kDA

Genomic Context


Human

Location:	9p24.2
Sequence:	9; NC_000009.12 (2621786..2660056)

Tissue Specificity

Abundant in heart and skeletal muscle; also ovary and kidney; not in liver.

Subcellular Localizations

Membrane; Single-pass type I membrane protein. Membrane, clathrin-coated pit; Single-pass type I membrane protein.

Diseases

Alzheimer's Disease
Malignant Neoplasms
Atherosclerosis
Nervousness
Hypoplasia
Congenital Cerebellar Hypoplasia
Lissencephaly
Neoplasms
Hyperlipidemia
Hypercholesterolemia
Ataxia
Arteriosclerosis

Pathologic Neovascularization
Schizophrenia
Tumor Angiogenesis
Retinal Neovascularization
Obesity
Cerebellar Ataxia
Hypercholesterolemia, Familial

Interacting Proteins

LRPAP1
Lrpap1
Reln

Pathways

Transport
Brain Development
Endocytosis
Pathogenesis
Cell Proliferation
Localization
Angiogenesis
Cholesterol Homeostasis
Lipid Transport
Locomotion
Neuroblast Migration
Secretion
Cell Motility

Receptor-mediated Endocytosis
Methylation
Cell Death
Cell Migration
Myelination
Spermatogenesis
Cognition

PTMs

Phosphorylation
Cleavage
Methylation
Carboxylation
Glycosylation

Gamma-carboxylation
Oxidation
Acylation
Ribosylation
Ubiquitination

Research Areas

Apoptosis
Cholesterol Metabolism
Lipid and Metabolism
Neurodegeneration
Neuronal Cell Markers

Neuroscience

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/VLDLR

References

PMID: 8128315 by Gafvels M.E., et al. Cloning of a cDNA encoding a putative human very low density lipoprotein/apolipoprotein E receptor and assignment of the gene to chromosome 9pter-p23.

PMID: 8069294 by Webb J.C., et al. Characterization and tissue-specific expression of the human 'very low density lipoprotein (VLDL) receptor' mRNA.