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- Table of Contents
VLDLR Antibodies
AND VLDLR ELISA kits, VLDLR Proteins
Many biological assays use antibodies to detect VLDLR, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with VLDLR in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop VLDLR antibodies...
Designing a Western blot for VLDLR? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the VLDLR Western Blot GuideVLDLR Infographic by Boster Bio
All VLDLR Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, WB
$370
Cat # A02195-1
100 μg/vial
Cat # A02195-1
100 μg/vial
Human
$960
Cat # LS007436
20 µg, 100 µg
Cat # LS007436
20 µg, 100 µg
VLDLR Overview
Facts about Very low-density lipoprotein receptor.
Very low-density lipoprotein receptor (VLDLR)
Binds VLDL and transports it into cells by endocytosis. So as to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits.
Binding to Reelin induces tyrosine phosphorylation of Dab1 and modulation of Tau phosphorylation (By similarity). .
Gene Information
| Human | |
|---|---|
| Gene Name: | VLDLR |
| Uniprot: | P98155 |
| Entrez: | 7436 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
CARMQ1; CHRMQ1; FLJ35024; very low density lipoprotein receptor; very low-density lipoprotein receptor; VLDL R; VLDL receptor; VLDLR; VLDL-R; VLDLRCH
Molecular Weight
Mass (kDA):
96.098 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 9p24.2 |
| Sequence: | 9; NC_000009.12 (2621786..2660056) |
Tissue Specificity
Abundant in heart and skeletal muscle; also ovary and kidney; not in liver.
Subcellular Localizations
Membrane; Single-pass type I membrane protein. Membrane, clathrin-coated pit; Single-pass type I membrane protein.
Diseases
- Alzheimer's Disease
- Malignant Neoplasms
- Atherosclerosis
- Nervousness
- Hypoplasia
- Congenital Cerebellar Hypoplasia
- Lissencephaly
- Neoplasms
- Hyperlipidemia
- Hypercholesterolemia
- Ataxia
- Arteriosclerosis
Interacting Proteins
- LRPAP1
- Lrpap1
- Reln
Pathways
- Transport
- Brain Development
- Endocytosis
- Pathogenesis
- Cell Proliferation
- Localization
- Angiogenesis
- Cholesterol Homeostasis
- Lipid Transport
- Locomotion
- Neuroblast Migration
- Secretion
- Cell Motility
PTMs
- Phosphorylation
- Cleavage
- Methylation
- Carboxylation
- Glycosylation
Research Areas
- Apoptosis
- Cholesterol Metabolism
- Lipid and Metabolism
- Neurodegeneration
- Neuronal Cell Markers
- Neuroscience
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/VLDLR
bosterbio.com/bosterbio-gene-info-cards/VLDLR
References
PMID: 8128315 by Gafvels M.E., et al. Cloning of a cDNA encoding a putative human very low density lipoprotein/apolipoprotein E receptor and assignment of the gene to chromosome 9pter-p23.
PMID: 8069294 by Webb J.C., et al. Characterization and tissue-specific expression of the human 'very low density lipoprotein (VLDL) receptor' mRNA.