VNN2 Antibodies

AND VNN2 ELISA kits, VNN2 Proteins

Many biological assays use antibodies to detect VNN2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with VNN2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop VNN2 antibodies...

We validate the specificity of these antibodies to VNN2 by testing them on tissues known to express VNN2 positively and negatively. Browse below to find the VNN2 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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VNN2 Infographic by Boster Bio

All VNN2 Products

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Product

Figures

Specificity

Applications

Price

Anti-VNN2 Antibody

Human

ELISA, WB

$380
Cat # A08030
100ul

VNN2 (NM_078488) Human Over-expression Lysate

Human

$960
Cat # LS008875
20 µg, 100 µg

VNN2 Overview

Facts about Vascular non-inflammatory molecule 2.

VNN2 3D structure. Source: alphafold

Vascular non-inflammatory molecule 2 (VNN2)

Amidohydrolase that hydrolyzes specifically among those carboamide linkages in D-pantetheine thus recycling pantothenic acid (vitamin B5) and discharging cysteamine. Involved in the thymus homing of bone marrow cells.

May govern beta-2 integrin-mediated cell adhesion, migration and motility of neutrophil. .

Gene Information

Human
Gene Name:	VNN2
Uniprot:	O95498
Entrez:	8875

Family

Belongs to:

carbon-nitrogen hydrolase superfamily

Alternative Names

EC 3.5.1; EC 3.5.1.92; FOAP-4; Glycosylphosphatidyl inositol-anchored protein GPI-80; GPI-80 variant protein 1; GPI-80 variant protein 2; GPI-80 variant protein 3; GPI-80 variant protein 4; GPI-80; pantetheinase; Protein FOAP-4; vanin 2; vanin-2; Vannin 2; vascular non-inflammatory molecule 2

Molecular Weight

Mass (kDA):
58.503 kDA

Genomic Context


Human

Location:	6q23.2
Sequence:	6; NC_000006.12 (132743503..132763489, complement)

Tissue Specificity

Widely expressed with higher expression in spleen and blood.

Subcellular Localizations

Cell membrane; Lipid-anchor, GPI-anchor.

Diseases

Tissue Adhesions
Inflammation
Extravasation
Rheumatoid Arthritis
Arthritis
Malignant Neoplasms
Neoplasm Metastasis
Metastatic Malignant Neoplasm To The Lymph Node
Thymus Neoplasms
Dermatitis, Atopic
Inflammatory Bowel Diseases
Thymoma

Coronary Artery Disease
Intestinal Diseases
Carcinoma
Paroxysmal Nocturnal Hemoglobinuria
Neoplasms
Acute Promyelocytic Leukemia
Pertussis

Pathways

Cell Adhesion
Localization
Neutrophil Extravasation
Lymphocyte Migration
Neutrophil Activation
Cell Cycle
Cell Activation
Neutrophil Differentiation
Immune Response
Ovulation

Reverse Transcription
Phagocytosis
Locomotion
Secretion

PTMs

Phosphorylation

Cleavage

Oxidation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/VNN2

References

PMID: 9790769 by Galland F., et al. Two human genes related to murine vanin-1 are located on the long arm of human chromosome 6.

PMID: 10201959 by Suzuki K., et al. A novel glycosylphosphatidyl inositol-anchored protein on human leukocytes: a possible role for regulation of neutrophil adherence and migration.