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- Table of Contents
Facts about Visual system homeobox 1.
.
Human | |
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Gene Name: | VSX1 |
Uniprot: | Q9NZR4 |
Entrez: | 30813 |
Belongs to: |
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paired homeobox family |
Visual system homeobox 1
Mass (kDA):
38.431 kDA
Human | |
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Location: | 20p11.21 |
Sequence: | 20; NC_000020.11 (25069940..25082141, complement) |
In the adult eye, expressed in lens, iris, ciliary body, choroid, optical nerve head and, most strongly, in retina, but not expressed in sclera and cornea. According to PubMed:11978762, expressed in adult retina but not in lens and cornea. Within adult retina, found exclusively in the inner nuclear layer. Isoform 1, isoform 2, isoform 3 and isoform 4 expressed in adult retina, but not in brain, heart, kidney, liver, lung, pancreas, placenta and skeletal muscle. Not expressed in thymus and spleen. Expressed in embryonic craniofacial tissue. Expressed in fetal (week 14) retina. Strongly expressed in neonatal retina (day 0), weakly in neonatal lens (day 0), choroid (day 0) and cornea (day 0, 4; month 9).
Nucleus.
PMID: 10673340 by Semina E.V., et al. Isolation and characterization of a novel human paired-like homeodomain-containing transcription factor gene, VSX1, expressed in ocular tissues.
PMID: 10903837 by Hayashi T., et al. RINX(VSX1), a novel homeobox gene expressed in the inner nuclear layer of the adult retina.