Vwc2l Antibodies

AND Vwc2l ELISA kits, Vwc2l Proteins

Many biological assays use antibodies to detect Vwc2l, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Vwc2l in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Vwc2l antibodies...

We validate the specificity of these antibodies to Vwc2l by testing them on tissues known to express Vwc2l positively and negatively. Browse below to find the Vwc2l antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Vwc2l Infographic by Boster Bio

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VWC2L (NM_001080500) Human Over-expression Lysate

Human

$628
Cat # LS402117
20 µg, 100 µg

Vwc2l Overview

Facts about von Willebrand factor C domain-containing protein 2-like.

von Willebrand factor C domain-containing protein 2-like (Vwc2l)

May play a role in neurogenesis. May promote matrix mineralization (PubMed:22209847), but has been shown to weakly, but significantly inhibit BMP2 and BMP6 activity in a preosteoblastic cell line (PubMed:19852960).

Gene Information

Mouse
Gene Name:	Vwc2l
Uniprot:	Q505H4
Entrez:	320460

Family

Belongs to:

No superfamily

Alternative Names

brorin-like; von Willebrand factor C domain containing protein 2-like; von Willebrand factor C domain-containing protein 2-like

Molecular Weight

Mass (kDA):
24.528 kDA

Genomic Context


Mouse

Location:	1\|1 C3
Sequence:	1;

Tissue Specificity

Predominantly expressed in the brain (at protein level). Also detected in bones, including femur and calvaria, heart, lung and kidney. Isoform 5 is predominant in lung and heart, compared to isoforms 1 and 3. Isoform 4 is expressed in femur and calvaria at higher levels than isoforms 1 and 5. Isoforms 1 and 4 are expressed at higher levels than isoform 5 in kidney and brain.

Diseases

Von Willebrand Disease

Pathways

Regeneration

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Vwc2l

References

PMID: 19852960 by Miwa H., et al. A novel neural-specific BMP antagonist, Brorin-like, of the Chordin family.

PMID: 22209847 by Ohyama Y., et al. Modulation of matrix mineralization by Vwc2-like protein and its novel splicing isoforms.