WASH2P Antibodies

AND WASH2P ELISA kits, WASH2P Proteins

Many biological assays use antibodies to detect WASH2P, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with WASH2P in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop WASH2P antibodies...

We validate the specificity of these antibodies to WASH2P by testing them on tissues known to express WASH2P positively and negatively. Browse below to find the WASH2P antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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WASH2P Infographic by Boster Bio

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WASH2P Overview

Facts about WAS protein family homolog 2.

WASH2P 3D structure. Source: alphafold

WAS protein family homolog 2 (WASH2P)

Acts as a nucleation-promoting factor at the surface of endosomes, where it recruits and activates the Arp2/3 complex to induce actin polymerization, playing a key role in the fission of tubules that serve as transport intermediates during endosome sorting. Involved in endocytic trafficking of EGF.

Its assembly in the WASH core complex appears to inhibit its NPF activity and through WASHC2 is required for its membrane targeting. Involved in transferrin receptor recycling.

Gene Information

Human
Gene Name:	WASH2P
Uniprot:	Q6VEQ5
Entrez:	375260

Family

Belongs to:

WASH1 family

Alternative Names

WAS protein family homolog 2

Molecular Weight

Mass (kDA):
50.312 kDA

Genomic Context


Human

Location:	2q14.1
Sequence:	2; NC_000002.12 (113583653..113599037)

Subcellular Localizations

Early endosome membrane. Recycling endosome membrane. Late endosome. Cytoplasmic vesicle, autophagosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Localization to the endosome membrane is mediated via its interaction with WASHC2.

PTMs

Isopeptide bond

Ubl conjugation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/WASH2P

References

PMID: 15233989 by Wong A., et al. Diverse fates of paralogs following segmental duplication of telomeric genes.

PMID: 10655549 by Ciccodicola A., et al. Differentially regulated and evolved genes in the fully sequenced Xq/Yq pseudoautosomal region.