WASH3P Antibodies

AND WASH3P ELISA kits, WASH3P Proteins

Many biological assays use antibodies to detect WASH3P, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with WASH3P in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop WASH3P antibodies...

We validate the specificity of these antibodies to WASH3P by testing them on tissues known to express WASH3P positively and negatively. Browse below to find the WASH3P antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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WASH3P Infographic by Boster Bio

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WASH3P Overview

Facts about Putative WAS protein family homolog 3.

WASH3P 3D structure. Source: alphafold

Putative WAS protein family homolog 3 (WASH3P)

Acts as a nucleation-promoting factor in the surface of endosomes, where it recruits and activates the Arp2/3 complex to induce actin polymerization, playing a key role in the fission of tubules that function as transport intermediates during endosome sorting (PubMed:18159949, PubMed:20175130). Its assembly in the WASH core complex seems to inhibit its NPF activity and through WASHC2 is required for its membrane targeting.

Involved in transferrin receptor recycling. Regulates the trafficking of endosomal alpha5beta1 integrin into the plasma membrane and involved in invasive cell migration (By similarity).

Gene Information

Human
Gene Name:	WASH3P
Uniprot:	C4AMC7
Entrez:	374666

Family

Belongs to:

WASH1 family

Alternative Names

Putative WAS protein family homolog 3

Molecular Weight

Mass (kDA):
49.995 kDA

Genomic Context


Human

Location:	15q26.3
Sequence:	15; NC_000015.10 (101960813..101976605)

Subcellular Localizations

Early endosome. Early endosome membrane. Recycling endosome membrane. Cell projection, lamellipodium. Cell projection, filopodium. Cytoplasmic vesicle, autophagosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Localization to the endosome membrane is mediated via its interaction with WASHC2. Localizes to MMP14-positive late endosomes and transiently to invadipodia (By similarity). Localized to Salmonella typhimurium entry sites (By similarity).

PTMs

Isopeptide bond

Ubl conjugation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/WASH3P

References

PMID: 10655549 by Ciccodicola A., et al. Differentially regulated and evolved genes in the fully sequenced Xq/Yq pseudoautosomal region.

PMID: 18159949 by Linardopoulou E.V., et al. Human subtelomeric WASH genes encode a new subclass of the WASP family.