WDFY1 Antibodies

AND WDFY1 ELISA kits, WDFY1 Proteins

Many biological assays use antibodies to detect WDFY1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with WDFY1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop WDFY1 antibodies...

We validate the specificity of these antibodies to WDFY1 by testing them on tissues known to express WDFY1 positively and negatively. Browse below to find the WDFY1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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WDFY1 Infographic by Boster Bio

All WDFY1 Products

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Product

Figures

Specificity

Applications

Price

FENS1 (WDFY1) (NM_020830) Human Recombinant Protein

Coomassie blue staining of purified WDFY1 protein

$1062
Cat # PROTQ8IWB7
20 µg

Anti-FENS1/WDFY1 Antibody Picoband®

Western blot analysis of FENS1/WDFY1 using anti-FENS1/WDFY1 antibody (A10318-3)

Flow Cytometry analysis of HL-60 cells using anti-FENS1/WDFY1 antibody (A10318-3)

Human, Mouse, Rat

ELISA, Flow Cytometry, WB

$370
Cat # A10318-3
100 μg/vial

FENS1 (WDFY1) (NM_020830) Human Over-expression Lysate

Human

$628
Cat # LS057590
20 µg, 100 µg

WDFY1 Overview

Facts about WD repeat and FYVE domain-containing protein 1.

WDFY1 3D structure. Source: alphafold

WD repeat and FYVE domain-containing protein 1 (WDFY1)

Positively regulates TLR3- and TLR4-mediated signaling pathways by bridging the interaction between TLR3 or TLR4 and TICAM1.
Promotes TLR3/4 ligand-induced activation of transcription factors IRF3 and NF-kappa-B, in addition to the creation of IFN-beta and inflammatory cytokines (PubMed:25736436).

Gene Information

Human
Gene Name:	WDFY1
Uniprot:	Q8IWB7
Entrez:	57590

Family

Belongs to:

No superfamily

Alternative Names

FENS-1Zinc finger FYVE domain-containing protein 17; KIAA1435; Phosphoinositide-binding protein 1; WD repeat and FYVE domain containing 1; WD repeat and FYVE domain-containing protein 1; WD40 and FYVE domain containing 1; WDF1WD40- and FYVE domain-containing protein 1; ZFYVE17phosphoinositide-binding protein SR1

Molecular Weight

Mass (kDA):
46.324 kDA

Genomic Context


Human

Location:	2q36.1
Sequence:	2; NC_000002.12 (223875348..223945335, complement)

Subcellular Localizations

Early endosome.

Diseases

Cell Invasion
Nerve Degeneration
Alzheimer's Disease

Pathways

Tissue Remodeling
Cell Differentiation
Rna Processing

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/WDFY1

References

PMID: 11739631 by Ridley S.H., et al. FENS-1 and DFCP1 are FYVE domain-containing proteins with distinct functions in the endosomal and Golgi compartments.

PMID: 19296456 by He J., et al. Membrane insertion of the FYVE domain is modulated by pH.