WDR12 Antibodies

AND WDR12 ELISA kits, WDR12 Proteins

Many biological assays use antibodies to detect WDR12, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with WDR12 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop WDR12 antibodies...

We validate the specificity of these antibodies to WDR12 by testing them on tissues known to express WDR12 positively and negatively. Browse below to find the WDR12 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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WDR12 Infographic by Boster Bio

All WDR12 Products

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Product

Figures

Specificity

Applications

Price

Anti-WDR12 Antibody

Western blot analysis of extracts of various cell lines, using WDR12 antibody at 1:1000 dilution

Human

$405
Cat # A07492
100ul

Anti-WDR12 Antibody Picoband®

Western blot analysis of WDR12 using anti-WDR12 antibody (A07492-1)

Flow Cytometry analysis of HL-60 cells using anti-WDR12 antibody (A07492-1)

Human

ELISA, Flow Cytometry, WB

$370
Cat # A07492-1
100 μg/vial

WDR12 (NM_018256) Human Over-expression Lysate

Human

$628
Cat # LS055759
20 µg, 100 µg

WDR12 Overview

Facts about Ribosome biogenesis protein WDR12.

WDR12 3D structure. Source: alphafold

Ribosome biogenesis protein WDR12 (WDR12)

Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.

Gene Information

Human
Gene Name:	WDR12
Uniprot:	Q9GZL7
Entrez:	55759

Family

Belongs to:

WD repeat WDR12/YTM1 family

Alternative Names

FLJ10881; FLJ12719; FLJ12720; ribosome biogenesis protein WDR12; WD repeat domain 12; WD repeat-containing protein 12; YTM1

Molecular Weight

Mass (kDA):
47.708 kDA

Genomic Context


Human

Location:	2q33.2
Sequence:	2; NC_000002.12 (202874261..202911673, complement)

Subcellular Localizations

Nucleus, nucleolus. Nucleus, nucleoplasm.

Diseases

Myocardial Infarction
Infarction
Hypertensive Disease
Hyperlipidemia
Coronary Artery Disease
Diabetes Mellitus

Interacting Proteins

BOP1
PES1

Pathways

Cell Proliferation
Localization
Rrna Processing
Ribosome Biogenesis
Cell Cycle
Transport
S Phase
Rna Processing

Rna Interference
Cell Cycle Arrest

PTMs

Acetylation
Isopeptide bond

Phosphoprotein
Ubl conjugation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/WDR12

References

PMID: 16043514 by Hoelzel M., et al. Mammalian WDR12 is a novel member of the Pes1-Bop1 complex and is required for ribosome biogenesis and cell proliferation.

PMID: 16738141 by Grimm T., et al. Dominant-negative Pes1 mutants inhibit ribosomal RNA processing and cell proliferation via incorporation into the PeBoW-complex.