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- Table of Contents

Facts about WD repeat domain phosphoinositide-interacting protein 3.
| Human | |
|---|---|
| Gene Name: | WDR45B |
| Uniprot: | Q5MNZ6 |
| Entrez: | 56270 |

| Belongs to: |
|---|
| WD repeat SVP1 family |

WD repeat domain phosphoinositide-interacting protein 3
Mass (kDA):
38.122 kDA

| Human | |
|---|---|
| Location: | 17q25.3 |
| Sequence: | 17; NC_000017.11 (82614562..82648530, complement) |
Ubiquitously expressed. Highly expressed in heart, skeletal muscle and pancreas. Up-regulated in a variety of tumor tissues including ovarian and uterine cancers.
Preautophagosomal structure. Lysosome.


PMID: 28561066 by Bakula D., et al. WIPI3 and WIPI4 beta-propellers are scaffolds for LKB1-AMPK-TSC signalling circuits in the control of autophagy.
PMID: 15602573 by Proikas-Cezanne T., et al. WIPI-1alpha (WIPI49), a member of the novel 7-bladed WIPI protein family, is aberrantly expressed in human cancer and is linked to starvation-induced autophagy.