Protein Wnt-8a Antibodies

Protein Wnt-8a (WNT8A)

Ligand for members of the frizzled family of seven transmembrane receptors. Plays a role in embryonic patterning.

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Gene Information

Human
Gene Name:	WNT8A
Uniprot:	Q9H1J5
Entrez:	7478

Family

Belongs to:
Wnt family

Alternative Names

protein Wnt-8a; Protein Wnt-8d; wingless-type MMTV integration site family, member 8A; Wnt8a; Wnt-8a; WNT8DWNT8d

Molecular Weight

Mass (kDA):
38.849 kDA

Genomic Context

Human
Location:	5q31.2
Sequence:	5; NC_000005.10 (138077367..138092900)

Subcellular Localizations

Secreted, extracellular space, extracellular matrix. Secreted.

Diseases

• Malignant Neoplasms
• Neoplasms
• Carcinogenesis
• Malignant Neoplasm Of Stomach
• Crest Syndrome
• Embryonal Carcinoma
• Nervousness
• Stomach Neoplasms
• Carcinoma
• Tissue Adhesions
• Malignant Neoplasm Of Breast
• Cleft Palate
• Malignant Neoplasm Of Pancreas

• Cleft Lip
• Congenital Abnormality
• Eye Abnormalities
• Colorectal Cancer
• Malignant Tumor Of Cervix
• Mammary Neoplasms
• Chimera Disorder

Pathways

• Gastrulation
• Mesoderm Formation
• Axis Specification
• Glycosylation
• Localization
• Cell Adhesion
• Somitogenesis
• Fertilization
• Cell Differentiation
• Cell-cell Adhesion
• Epiboly
• Translation
• Neural Crest Formation

• Cell Migration
• Developmental Process
• Oogenesis
• Cell Proliferation
• Ovulation
• Pathogenesis
• Transport

PTMs

• Phosphorylation
• Glycosylation

• Cleavage
• Dephosphorylation

• Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/WNT8A

The Best Uses Of The WNT8A Marker

Scientists who work with the WNT8A marker may be curious about the benefits of this protein. You will find information about the WNT8A markers uses, applications and resources. Additionally, you will learn how product credits can be used to support your work. These benefits apply to scientists all over the world. Read on to learn more about the WNT8A Marker and its benefits.

Benefits of using the WNT8A Marker

The WNT8A marker is a mRNA of the Wnt family 8A. It is involved throughout animal development, including gastrulation as well as regionalization and organ growth. It has been shown to be expressed in many structures and can be found in extracellular space. In addition, this mRNA is expressed by several cells and tissues. Although there are still questions regarding its functions in the body, it offers several advantages.

It is useful to use this method in clinical practice when assessing the progression of cancer. WNT ligands with an aberrant expression tend to promote cancer aggressiveness which can increase the risk for metastasis. WNT8A aberrantly expressed tumors have poor clinical outcomes and are generally more aggressive. WNT8A Marker can help predict the risk of tumor progression. It is based on WNT8B expression.

Applications

The WNT gene group encodes secreted signals proteins that are involved many developmental processes, such as oncogenesis. Moreover, they are involved in the patterning and regulation of cell fate. The WNT8A genes encode a protein with 81% similarity to the WNT8A genes of mice. It has several downstream targets that are crucial for development of animal limbs and human health.

Resources

The WNT8A marker is part of the Wnt family and is predicted to localize in the extracellular space. The WNT8A marker has been implicated in organ development, gastrulation, regionalization, and other biological processes. This marker is found in multiple structures and has been implicated for many developmental processes, including the oncogenesis process. It is unclear at this time what function it has in development. However, several biological processes involve it and it may play a role the differentiation or certain structures in your forebrain.

The WNT family of genes is composed structurally similar genes that encode secreted message molecules. This plays a role in both oncogenesis, and many developmental processes. WNT8A is implicated in cell fate regulation and patterning during embryogenesis. It is still being researched for its role in cancer research, but it has been implicated throughout many processes including cell growth and death. Many orthologs for the WNT gene group are found in other species.

PDFs

PDFs are one of the most common file types. Enhancing them is one of the best uses of the WNT8AMarker. The WNT8A Marker is used to markup PDFs. It can add text, images, or comment. The application can be accessed through any modern web browser and includes basic tools for annotations. Users can add and highlight text, as well as insert notes and make annotations. They can also add weblinks, forms fields, and other annotations.