Xaa-Pro aminopeptidase 3 Antibodies

AND XPNPEP3 ELISA kits, Xaa-Pro aminopeptidase 3 Proteins

Many biological assays use antibodies to detect Xaa-Pro aminopeptidase 3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Xaa-Pro aminopeptidase 3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Xaa-Pro aminopeptidase 3 antibodies...

We validate the specificity of these antibodies to Xaa-Pro aminopeptidase 3 by testing them on tissues known to express XPNPEP3 positively and negatively. Browse below to find the XPNPEP3 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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XPNPEP3 Infographic by Boster Bio

All XPNPEP3 Products

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Applications

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Anti-XPNPEP3 Mouse Monoclonal Antibody [Clone ID: OTI5G2]

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY XPNPEP3 (Right lane) cDNA for 48 hrs and lysed

Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-XPNPEP3 monoclonal antibody

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-XPNPEP3 mouse monoclonal antibody

Dog, Human, Monkey, Mouse, Rat

Flow Cytometry, IF, IHC, WB

$523
Cat # M11450
100 µl

XPNPEP3 (NM_022098) Human Over-expression Lysate

Human

$628
Cat # LS063929
20 µg, 100 µg

Anti-XPNPEP3 Antibody

Human, Mouse, Rat

ELISA, IP, IHC, WB

$370
Cat # A11450-1
100 μl/vial

XPNPEP3 Overview

Facts about Xaa-Pro aminopeptidase 3.

XPNPEP3 3D structure. Source: alphafold

Xaa-Pro aminopeptidase 3 (XPNPEP3)

Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides, such as Leu-Pro-Ala (PubMed:25609706, PubMed:28476889). Also shows low activity towards peptides with Ala or Ser in the P1 position (PubMed:28476889).

Gene Information

Human
Gene Name:	XPNPEP3
Uniprot:	Q9NQH7
Entrez:	63929

Family

Belongs to:

peptidase M24B family

Alternative Names

Aminopeptidase P3; APP3probable Xaa-Pro aminopeptidase 3; NPHPL1EC 3.4.11.9; X-Pro aminopeptidase 3; X-prolyl aminopeptidase (aminopeptidase P) 3, putative

Molecular Weight

Mass (kDA):
57.034 kDA

Genomic Context


Human

Location:	22q13.2
Sequence:	22; NC_000022.11 (40857081..40932815)

Tissue Specificity

Isoform 1 and isoform 2 are widely expressed, with isoform 1 being more abundant.

Subcellular Localizations

[Isoform 1]: Mitochondrion. Cytoplasm. Mainly mitochondrial. Translocates to the cytoplasm following TNFRSF1B activation.; [Isoform 2]: Cytoplasm.

Diseases

Cystic Kidney Diseases
Kidney Diseases
Nephronophthisis
Genetic Diseases, Inborn
Meckel-gruber Syndrome
Renal Insufficiency
Familial Aplasia Of The Vermis
Kidney Failure
Chronic Eosinophilic Leukemia
Diabetes Mellitus

Pancreatitis
Pancreatitis, Chronic
Renal Dysplasia And Retinal Aplasia (disorder)
Streptococcal Lymphadenitis Of Swine

Pathways

Localization

PTMs

Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/XPNPEP3

References

PMID: 15708373 by Ersahin C., et al. Aminopeptidase P isozyme expression in human tissues and peripheral blood mononuclear cell fractions.

PMID: 25609706 by Inoue M., et al. Aminopeptidase P3, a new member of the TNF-TNFR2 signaling complex, induces phosphorylation of JNK1 and JNK2.