YY1-associated factor 2 Antibodies

AND YAF2 ELISA kits, YY1-associated factor 2 Proteins

Many biological assays use antibodies to detect YY1-associated factor 2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with YY1-associated factor 2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop YY1-associated factor 2 antibodies...

We validate the specificity of these antibodies to YY1-associated factor 2 by testing them on tissues known to express YAF2 positively and negatively. Browse below to find the YAF2 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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YAF2 Infographic by Boster Bio

All YAF2 Products

Product

Figures

Specificity

Applications

Price

Anti-YY1-associated factor 2 YAF2 Antibody

Human, Mouse, Rat

$405
Cat # A08678
100ul

YY1 associated factor 2 (YAF2) (NM_005748) Human Recombinant Protein

$1249
Cat # PROTQ8IY57
20 µg

YY1 associated factor 2 (YAF2) (NM_005748) Human Over-expression Lysate

Human

$628
Cat # LS010138
100 µg

Anti-YAF2 Antibody Picoband™

Human

ELISA, WB

$370
Cat # A08678-1
100 µg/vial

YAF2 Overview

Facts about YY1-associated factor 2.

YAF2 3D structure. Source: alphafold

YY1-associated factor 2 (YAF2)

Binds to MYC and inhibits MYC-mediated transactivation.
Also binds to MYCN and enhances MYCN-dependent transcriptional activation.

Increases calpain 2-mediated proteolysis of YY1 in vitro. Part of the E2F6.

Gene Information

Human
Gene Name:	YAF2
Uniprot:	Q8IY57
Entrez:	10138

Family

Belongs to:

No superfamily

Alternative Names

DKFZp779H1820; MGC41856; YY1 associated factor 2; YY1-associated factor 2

Molecular Weight

Mass (kDA):
19.901 kDA

Genomic Context


Human

Location:	12q12
Sequence:	12; NC_000012.12 (42157104..42238373, complement)

Subcellular Localizations

Nucleus.

Diseases

Neuroblastoma
Clinodactyly
Cell Transformation, Neoplastic
Strabismus
Developmental Delay (disorder)
Cleft Palate
Physiological Stress
Osteosarcoma
Fibrosis

Malignant Neoplasms
Chimera Disorder
Cytogenetic Abnormality
Hyperplasia

Interacting Proteins

RING1
SETBP1
XAGE1A

Pathways

Localization
Cell Proliferation
Cell Cycle
Cell Death
Proteolysis
Stem Cell Maintenance

PTMs

Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/YAF2

References

PMID: 9016636 by Kalenik J.L., et al. Yeast two-hybrid cloning of a novel zinc finger protein that interacts with the multifunctional transcription factor YY1.

PMID: 11593398 by Bannasch D., et al. Functional interaction of Yaf2 with the central region of MycN.