Zfp36l3 Antibodies

AND Zfp36l3 ELISA kits, Zfp36l3 Proteins

Many biological assays use antibodies to detect Zfp36l3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Zfp36l3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Zfp36l3 antibodies...

We validate the specificity of these antibodies to Zfp36l3 by testing them on tissues known to express Zfp36l3 positively and negatively. Browse below to find the Zfp36l3 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Zfp36l3 Infographic by Boster Bio

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Zfp36l3 Overview

Facts about mRNA decay activator protein ZFP36L3.

Zfp36l3 3D structure. Source: alphafold

mRNA decay activator protein ZFP36L3 (Zfp36l3)

Placenta-specific zinc-finger RNA-binding protein that destabilizes cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis (PubMed:15814898, PubMed:26952984). Binds to the 3'-UTR ARE of placental target mRNAs, such as TNF, HBEGF and LIPG (PubMed:15814898, PubMed:18367448, PubMed:26952984).

Involved in placental expression of several genes important for normal placental physiology (PubMed:26952984). .

Gene Information

Mouse
Gene Name:	Zfp36l3
Uniprot:	Q5ISE2
Entrez:	333473

Family

Belongs to:

No superfamily

Alternative Names

mRNA decay activator protein ZFP36L3

Molecular Weight

Mass (kDA):
72.346 kDA

Genomic Context


Mouse

Location:	X\|X A5
Sequence:	X;

Tissue Specificity

Expressed in placenta and extraembryonic tissues (at protein level). Not detected in embryos and fetus (PubMed:15814898, PubMed:26952984).

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Zfp36l3

References

PMID: 15814898 by Blackshear P.J., et al. Zfp36l3, a rodent X chromosome gene encoding a placenta-specific member of the Tristetraprolin family of CCCH tandem zinc finger proteins.

PMID: 18367448 by Frederick E.D., et al. A unique C-terminal repeat domain maintains the cytosolic localization of the placenta-specific tristetraprolin family member ZFP36L3.