ZFYVE28 Antibodies

AND ZFYVE28 ELISA kits, ZFYVE28 Proteins

Many biological assays use antibodies to detect ZFYVE28, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ZFYVE28 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ZFYVE28 antibodies...

We validate the specificity of these antibodies to ZFYVE28 by testing them on tissues known to express ZFYVE28 positively and negatively. Browse below to find the ZFYVE28 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ZFYVE28 Infographic by Boster Bio

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ZFYVE28 Overview

Facts about Lateral signaling target protein 2 homolog.

ZFYVE28 3D structure. Source: alphafold

Lateral signaling target protein 2 homolog (ZFYVE28)

Negative regulator of epidermal growth factor receptor (EGFR) signaling. Acts by boosting EGFR degradation in endosomes when not monoubiquitinated.

Gene Information

Human
Gene Name:	ZFYVE28
Uniprot:	Q9HCC9
Entrez:	57732

Family

Belongs to:

lst-2 family

Alternative Names

hLst2; KIAA1643; lateral signaling target protein 2 homolog; LST2; LYST2; MGC43699; MGC61592; Zinc finger FYVE domain-containing protein 28; zinc finger, FYVE domain containing 28

Molecular Weight

Mass (kDA):
96.49 kDA

Genomic Context


Human

Location:	4p16.3
Sequence:	4; NC_000004.12 (2269585..2418698, complement)

Subcellular Localizations

Cytoplasm, cytosol. Early endosome membrane. Localizes to early endosome membrane in absence of Lys-87 monoubiquitination. Localizes to cytosol when monoubiquitinated.

Diseases

Trematode Infections

Pathways

Localization

PTMs

Isopeptide bond

Phosphoprotein

Ubl conjugation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ZFYVE28

References

PMID: 19460345 by Mosesson Y., et al. Monoubiquitinylation regulates endosomal localization of Lst2, a negative regulator of EGF receptor signaling.