ZMPSTE24 Antibodies

AND ZMPSTE24 ELISA kits, ZMPSTE24 Proteins

Many biological assays use antibodies to detect ZMPSTE24, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ZMPSTE24 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ZMPSTE24 antibodies...

We validate the specificity of these antibodies to ZMPSTE24 by testing them on tissues known to express ZMPSTE24 positively and negatively. Browse below to find the ZMPSTE24 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ZMPSTE24 Infographic by Boster Bio

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ZMPSTE24 Overview

Facts about CAAX prenyl protease 1 homolog.

CAAX prenyl protease 1 homolog (ZMPSTE24)

Proteolytically removes the C-terminal three residues of farnesylated proteins. Acts on lamin A/C.

Gene Information

Human
Gene Name:	ZMPSTE24
Uniprot:	O75844
Entrez:	10269

Family

Belongs to:

peptidase M48A family

Alternative Names

zona pellucida binding protein 2; zona pellucida-binding protein 2; ZPBP-like protein; ZPBPLMGC41930

Molecular Weight

Mass (kDA):
54.813 kDA

Genomic Context


Human

Location:	1p34.2
Sequence:	1; NC_000001.11 (40258078..40294180)

Tissue Specificity

Widely expressed. High levels in kidney, prostate, testis and ovary.

Subcellular Localizations

Endoplasmic reticulum membrane; Multi-pass membrane protein. Nucleus inner membrane; Multi-pass membrane protein.

Diseases

Progeria
Premature Aging Syndrome
Lipodystrophy
Dysplasia
Mandibuloacral Dysostosis
Skin Abnormalities
Acquired Partial Lipodystrophy
Familial Generalized Lipodystrophy
Growth Retardation
Muscle Contracture
Hypoplasia
Acro-osteolysis

Fetal Growth Retardation
Dermatologic Disorders
Hiv Infections
Hereditary Diseases
Familial Partial Lipodystrophy
Skin Diseases, Genetic

Pathways

Aging
Senescence
Mating
Methylation
Prenylation
Pathogenesis
Dna Repair
Mitosis
Localization
Chromatin Organization
Cell Proliferation
Cellular Senescence
Autophagy

Response To Oxidative Stress
Dna Methylation
Protein Farnesylation
Cellular Homeostasis
Cell Cycle
Cell Death
Cell Growth

PTMs

Farnesylation
Cleavage
Prenylation
Methylation

Acetylation
Geranylgeranylation
Phosphorylation
Reduction

Research Areas

Angiogenesis
Cancer
Cell Biology
Cellular Markers
Extracellular Matrix

Signal Transduction
Ubiquitin Proteasome Pathway

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ZMPSTE24

References

PMID: 10076063 by Kumagai H., et al. Identification of a human cDNA encoding a novel protein structurally related to the yeast membrane-associated metalloprotease, Ste24p.

PMID: 9700155 by Tam A., et al. Dual roles for Ste24p in yeast a-factor maturation: NH2-terminal proteolysis and COOH-terminal CAAX processing.