Zinc finger protein 516 Antibodies

AND ZNF516 ELISA kits, Zinc finger protein 516 Proteins

Many biological assays use antibodies to detect Zinc finger protein 516, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Zinc finger protein 516 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Zinc finger protein 516 antibodies...

We validate the specificity of these antibodies to Zinc finger protein 516 by testing them on tissues known to express ZNF516 positively and negatively. Browse below to find the ZNF516 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ZNF516 Infographic by Boster Bio

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ZNF516 (NM_014643) Human Over-expression Lysate

Human

$960
Cat # LS009658
20 µg, 100 µg

ZNF516 Overview

Facts about Zinc finger protein 516.

ZNF516 3D structure. Source: alphafold

Zinc finger protein 516 (ZNF516)

Transcriptional regulator that binds to the promoter and activates the transcription of genes promoting brown adipose tissue (BAT) differentiation. Among brown adipose tissue-specific genes, binds the proximal region of the promoter of the UCP1 gene to activate its transcription and thus regulate thermogenesis (By similarity).

May also play a role in the cellular response to replication stress (PubMed:23446422). .

Gene Information

Human
Gene Name:	ZNF516
Uniprot:	Q92618
Entrez:	9658

Family

Belongs to:

krueppel C2H2-type zinc-finger protein family

Alternative Names

HsT287; KIAA0222; zinc finger protein 516

Molecular Weight

Mass (kDA):
124.289 kDA

Genomic Context


Human

Location:	18q23
Sequence:	18; NC_000018.10 (76357682..76495255, complement)

Subcellular Localizations

Nucleus.

Diseases

Haploinsufficiency
Chromosomal Deletion
Atresia
Conductive Hearing Loss

PTMs

Isopeptide bond

Ubl conjugation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ZNF516

References

PMID: 23446422 by Burrell R.A., et al. Replication stress links structural and numerical cancer chromosomal instability.

PMID: 25578880 by Dempersmier J., et al. Cold-inducible Zfp516 activates UCP1 transcription to promote browning of white fat and development of brown fat.