Zinc finger protein 580 Antibodies

AND ZNF580 ELISA kits, Zinc finger protein 580 Proteins

Many biological assays use antibodies to detect Zinc finger protein 580, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Zinc finger protein 580 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Zinc finger protein 580 antibodies...

We validate the specificity of these antibodies to Zinc finger protein 580 by testing them on tissues known to express ZNF580 positively and negatively. Browse below to find the ZNF580 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ZNF580 Infographic by Boster Bio

All ZNF580 Products

Product

Figures

Specificity

Applications

Price

ZNF580 (NM_016202) Human Recombinant Protein

$1249
Cat # PROTQ9UK33
20 µg

ZNF580 (NM_016202) Human Over-expression Lysate

Human

$628
Cat # LS051157
100 µg

ZNF580 Overview

Facts about Zinc finger protein 580.

ZNF580 3D structure. Source: alphafold

Zinc finger protein 580 (ZNF580)

Involved in the regulation of endothelial cell proliferation and migration. Mediates H(2)O(2)-induced leukocyte chemotaxis by elevating interleukin-8 creation and may play a role in inflammation.

May be involved in transcriptional regulation. .

Gene Information

Human
Gene Name:	ZNF580
Uniprot:	Q9UK33
Entrez:	51157

Family

Belongs to:

No superfamily

Alternative Names

LDL induced EC protein; LDL-induced EC protein; zinc finger protein 580

Molecular Weight

Mass (kDA):
18.756 kDA

Genomic Context


Human

Location:	19q13.42
Sequence:	19; NC_000019.10 (55641002..55643470)

Tissue Specificity

Expressed in endothelial cells.

Subcellular Localizations

Nucleus. Colocalized with SMAD2 in the nucleus.

Diseases

Tumor Angiogenesis
Leukemia
Monocytic Leukemia
Inflammation
Acute Monocytic Leukemia
Atherosclerosis

Inflammatory Response

Pathways

Angiogenesis
Inflammatory Response

PTMs

Isopeptide bond

Ubl conjugation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ZNF580

References

PMID: 20382120 by Sun H.Y., et al. Sphingosine-1-phosphate induces human endothelial VEGF and MMP-2 production via transcription factor ZNF580: novel insights into angiogenesis.

PMID: 21599657 by Luo Y., et al. ZNF580, a novel C2H2 zinc-finger transcription factor, interacts with the TGF-beta signal molecule Smad2.