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Zinc finger protein 746 Antibodies
AND ZNF746 ELISA kits, Zinc finger protein 746 Proteins
Many biological assays use antibodies to detect Zinc finger protein 746, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Zinc finger protein 746 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Zinc finger protein 746 antibodies...
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ZNF746 Overview
Facts about Zinc finger protein 746.
Zinc finger protein 746 (ZNF746)
Transcription repressor that specifically binds to the 5'-TATTTT[T/G]-3' consensus sequence on promoters and repress transcription of PGC-1-alpha (PPARGC1A), thereby playing a role in regulation of neuron death. .
Gene Information
| Human | |
|---|---|
| Gene Name: | ZNF746 |
| Uniprot: | Q6NUN9 |
| Entrez: | 155061 |
Family
| Belongs to: |
|---|
| krueppel C2H2-type zinc-finger protein family |
Alternative Names
FLJ31413; PARIS; Parkin-interacting sustrate; zinc finger protein 746
Molecular Weight
Mass (kDA):
69.136 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 7q36.1 |
| Sequence: | 7; NC_000007.14 (149472696..149497832, complement) |
Subcellular Localizations
Cytoplasm. Nucleus. Mainly localizes to the cytoplasm; probably translocates to the nucleus to repress selected genes.
Diseases
- Nerve Degeneration
- Parkinson Disease
- Neurodegenerative Disorders
Interacting Proteins
- PRKN
PTMs
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ZNF746
bosterbio.com/bosterbio-gene-info-cards/ZNF746
References
PMID: 21376232 by Shin J.H., et al. PARIS (ZNF746) repression of PGC-1alpha contributes to neurodegeneration in Parkinson's disease.