Zinc finger protein 93 Antibodies

AND ZNF93 ELISA kits, Zinc finger protein 93 Proteins

Many biological assays use antibodies to detect Zinc finger protein 93, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Zinc finger protein 93 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Zinc finger protein 93 antibodies...

We validate the specificity of these antibodies to Zinc finger protein 93 by testing them on tissues known to express ZNF93 positively and negatively. Browse below to find the ZNF93 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ZNF93 Infographic by Boster Bio

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ZNF93 Overview

Facts about Zinc finger protein 93.

ZNF93 3D structure. Source: alphafold

Zinc finger protein 93 (ZNF93)

Transcription factor specifically required to repress long interspersed nuclear element 1 (L1) retrotransposons: recognizes and binds L1 sequences and repress their expression by recruiting a repressive complex containing TRIM28/KAP1 (PubMed:25274305). Unable to repress expression of subtypes of L1 elements.

Binds to the 5' end of L1PA4, L1PA5 and L1PA6 subtypes, and some L1PA3 subtypes. Does not bind to L1PA7 or older subtypes nor at the most recently evolved L1PA2 and L1Hs.

Gene Information

Human
Gene Name:	ZNF93
Uniprot:	P35789
Entrez:	81931

Family

Belongs to:

krueppel C2H2-type zinc-finger protein family

Alternative Names

HPF34; HTF34; TF34; zinc finger protein 505; zinc finger protein 93; zinc finger protein HTF34; ZNF505

Molecular Weight

Mass (kDA):
70.971 kDA

Genomic Context


Human

Location:	19p12
Sequence:	19; NC_000019.10 (19900946..19935575)

Subcellular Localizations

Nucleus.

Diseases

Chondrosarcoma
Malignant Neoplasms
Neoplasms
Malignant Neoplasm Of Ovary
Ewings Sarcoma-primitive Neuroectodermal Tumor (pnet)
Sarcoma

Pathways

Drug Resistance

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ZNF93

References

PMID: 2023909 by Bellefroid E.J., et al. The evolutionarily conserved Kruppel-associated box domain defines a subfamily of eukaryotic multifingered proteins.

PMID: 19742314 by Duan Z., et al. ZNF93 increases resistance to ET-743 (Trabectedin; Yondelis) and PM00104 (Zalypsis) in human cancer cell lines.