ZRANB1 Antibodies

AND ZRANB1 ELISA kits, ZRANB1 Proteins

Many biological assays use antibodies to detect ZRANB1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ZRANB1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ZRANB1 antibodies...

We validate the specificity of these antibodies to ZRANB1 by testing them on tissues known to express ZRANB1 positively and negatively. Browse below to find the ZRANB1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ZRANB1 Infographic by Boster Bio

All ZRANB1 Products

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Anti-ZRANB1 Mouse Monoclonal Antibody [Clone ID: OTI7A3]

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ZRANB1 (Right lane) cDNA for 48 hrs and lysed

Immunohistochemical staining of paraffin-embedded Carcinoma of Human pancreas tissue using anti-ZRANB1 mouse monoclonal antibody

Immunohistochemical staining of paraffin-embedded Carcinoma of Human prostate tissue using anti-ZRANB1 mouse monoclonal antibody

Human, Mouse, Rat

IHC, WB

$523
Cat # M10897
100 µl

ZRANB1 (NM_017580) Human Over-expression Lysate

Human

$960
Cat # LS054764
20 µg, 100 µg

ZRANB1 Overview

Facts about Ubiquitin thioesterase ZRANB1.

ZRANB1 3D structure. Source: alphafold

Ubiquitin thioesterase ZRANB1 (ZRANB1)

Especially hydrolyzes'Lys-29'-linked and'Lys-33'- linked diubiquitin. Also cleaves'Lys-63'-linked chains, but with 40-fold less efficiency in contrast to'Lys-29'-linked ones.

Positive regulator of the Wnt signaling pathway that deubiquitinates APC protein, a negative regulator of Wnt-mediated transcription. Plays a role in the regulation of cell morphology and cytoskeletal organization.

Gene Information

Human
Gene Name:	ZRANB1
Uniprot:	Q9UGI0
Entrez:	54764

Family

Belongs to:

peptidase C64 family

Alternative Names

HRPE773; jacalin-like lectin domain containing 2; JCLN2; pancreatic adenocarcinoma upregulated factor; PAUF; PRO1567; Trabid; ZRANB1; zymogen granule protein 16 homolog B (rat); zymogen granule protein 16 homolog B

Molecular Weight

Mass (kDA):
80.967 kDA

Genomic Context


Human

Location:	10q26.13
Sequence:	10; NC_000010.11 (124939489..124988189)

Tissue Specificity

Widely expressed.

Subcellular Localizations

Cytoplasm. Nucleus. Enriched in punctate localization in the cytoplasm.

Diseases

Malignant Neoplasms
Down Syndrome
Huntington Disease

Interacting Proteins

PBLD
TBC1D3G
TRAF6
UBC

Pathways

Cell Migration

Research Areas

Cancer
DNA Repair
DNA replication, Transcription, Translation and Splicing

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ZRANB1

References

PMID: 11463333 by Evans P.C., et al. Isolation and characterization of two novel A20-like proteins.

PMID: 18281465 by Tran H., et al. Trabid, a new positive regulator of Wnt-induced transcription with preference for binding and cleaving K63-linked ubiquitin chains.