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- Table of Contents

Facts about U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2.
Recruited into U12 pre-mRNAs in an ATP- dependent manner and is required for assembly of the prespliceosome, a precursor to other spliceosomal complexes. For U2-type introns, it is selectively and specifically necessary for the next step of splicing.
| Human | |
|---|---|
| Gene Name: | ZRSR2 |
| Uniprot: | Q15696 |
| Entrez: | 8233 |

| Belongs to: |
|---|
| No superfamily |

CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2; Renal carcinoma antigen NY-REN-20; U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-relatedprotein 2; U2 small nuclear ribonucleoprotein auxiliary factor, small subunit 2; U2(RNU2) small nuclear RNA auxiliary factor 1-like 2MGC142014; U2AF1L2; U2AF1RS2MGC142040; U2AF1-RS2U2AF35-related protein; URPU2 small nuclear RNA auxiliary factor 1-like 2; zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2
Mass (kDA):
58.045 kDA

| Human | |
|---|---|
| Location: | Xp22.2 |
| Sequence: | X; NC_000023.11 (15790472..15826807) |
Widely expressed.
Nucleus.





PMID: 8586425 by Kitagawa K., et al. Isolation and mapping of human homologues of an imprinted mouse gene U2af1-rs1.
PMID: 9237760 by Tronchere H., et al. A protein related to splicing factor U2AF35 that interacts with U2AF65 and SR proteins in splicing of pre-mRNA.