Zinc finger protein ZXDC Antibodies

AND ZXDC ELISA kits, Zinc finger protein ZXDC Proteins

Many biological assays use antibodies to detect Zinc finger protein ZXDC, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Zinc finger protein ZXDC in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Zinc finger protein ZXDC antibodies...

We validate the specificity of these antibodies to Zinc finger protein ZXDC by testing them on tissues known to express ZXDC positively and negatively. Browse below to find the ZXDC antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ZXDC Infographic by Boster Bio

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ZXDC Overview

Facts about Zinc finger protein ZXDC.

ZXDC 3D structure. Source: alphafold

Zinc finger protein ZXDC (ZXDC)

Cooperates with CIITA to promote transcription of MHC class I and MHC class II genes. .

Gene Information

Human
Gene Name:	ZXDC
Uniprot:	Q2QGD7
Entrez:	79364

Family

Belongs to:

ZXD family

Alternative Names

dJ337O18.5; SWIM domain containing 1; zinc finger, SWIM-type containing 1

Molecular Weight

Mass (kDA):
89.988 kDA

Genomic Context


Human

Location:	3q21.3
Sequence:	3; NC_000003.12 (126437348..126475938, complement)

Tissue Specificity

Expressed at high levels in heart, kidney, liver and testis, at moderate levels in brain and stomach, and at low levels in lung, muscle, placenta, small intestine and spleen.

Subcellular Localizations

Nucleus.

Diseases

Neoplasms
Tumor Progression
Malignant Paraganglionic Neoplasm

Interacting Proteins

CIITA
WDR5
ZXDA

Pathways

Cell Proliferation
Cell Cycle

PTMs

Sumoylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ZXDC

References

PMID: 16600381 by Al-Kandari W., et al. ZXDC, a novel zinc finger protein that binds CIITA and activates MHC gene transcription.

PMID: 19777325 by Aleksandrova A., et al. An N- and C-terminal truncated isoform of zinc finger X-linked duplicated C protein represses MHC class II transcription.