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- Table of Contents
Uracil-DNA glycosylase Antibodies
AND UNG ELISA kits, Uracil-DNA glycosylase Proteins
Many biological assays use antibodies to detect Uracil-DNA glycosylase, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Uracil-DNA glycosylase in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Uracil-DNA glycosylase antibodies...
Designing a Western blot for Uracil-DNA glycosylase? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the UNG Western Blot GuideUNG Infographic by Boster Bio
All UNG Products
Product
Figures
Specificity
Applications
Price
Human, Monkey, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A01672-2
100 μg/vial
Cat # A01672-2
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M01672-2
100 μl/vial
Cat # M01672-2
100 μl/vial
UNG Overview
Facts about Uracil-DNA glycosylase.
Uracil-DNA glycosylase (UNG)
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. .
Gene Information
| Human | |
|---|---|
| Gene Name: | UNG |
| Uniprot: | P13051 |
| Entrez: | 7374 |
Family
| Belongs to: |
|---|
| uracil-DNA glycosylase (UDG) superfamily |
Alternative Names
DGU; DGUEC 3.2.2; HIGM4EC 3.2.2.27; UDG; UDGDKFZp781L1143; UNG; UNG15; UNG1uracil-DNA glycosylase 1, uracil-DNA glycosylase 2; UNG2; uracil-DNA glycosylase
Molecular Weight
Mass (kDA):
34.645 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 12q24.11 |
| Sequence: | 12; NC_000012.12 (109097597..109110992) |
Tissue Specificity
Isoform 1 is widely expressed with the highest expression in skeletal muscle, heart and testicles. Isoform 2 has the highest expression levels in tissues containing proliferating cells.
Subcellular Localizations
[Isoform 1]: Mitochondrion.; [Isoform 2]: Nucleus.
Diseases
- Malignant Neoplasms
- Infective Disorder
- Immunologic Deficiency Syndromes
- Hiv Infections
- Multiple Transition Abnormalities
- Neoplasms
- Hyperimmunoglobulin M Syndrome
- Tuberculosis
- Lymphoma
- Suppressor Mutation
- Cell Transformation, Neoplastic
- Carcinoma
Interacting Proteins
- RPA2
Pathways
- Dna Repair
- Mismatch Repair
- Dna Replication
- Cell Cycle
- Dna Deamination
- Pathogenesis
- Cell Proliferation
- Methylation
- Cell Death
- Base-excision Repair
- Immune Response
- Gene Conversion
- Dna Recombination
PTMs
- Deamination
- Cleavage
- Methylation
Research Areas
- Base Excision Repair
- Cancer
- DNA Repair
- Stem Cell Markers
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/UNG
bosterbio.com/bosterbio-gene-info-cards/UNG
References
PMID: 2555154 by Olsen L.C., et al. Molecular cloning of human uracil-DNA glycosylase, a highly conserved DNA repair enzyme.
PMID: 7926048 by Haug T., et al. Structure of the gene for human uracil-DNA glycosylase and analysis of the promoter function.