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- Table of Contents
PPID Antibodies
AND PPID ELISA kits, PPID Proteins
Many biological assays use antibodies to detect PPID, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PPID in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PPID antibodies...
Designing a Western blot for PPID? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the PPID Western Blot GuidePPID Infographic by Boster Bio
All PPID Products
Product
Figures
Specificity
Applications
Price
Human, Monkey, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M02424
100 μg/vial
Cat # M02424
100 μg/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A02424
100 μg/vial
Cat # A02424
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M02424-2
100 μl/vial
Cat # M02424-2
100 μl/vial
Human
$628
Cat # LS005481
20 µg, 100 µg
Cat # LS005481
20 µg, 100 µg
Enzyme Activity, SDS-PAGE
$275
Cat # PROTQ9CR16
Starting from 10ug
Cat # PROTQ9CR16
Starting from 10ug
Enzyme Activity, SDS-PAGE
$265
Cat # PROTQ08752
Starting from 20ug
Cat # PROTQ08752
Starting from 20ug
PPID Overview
Facts about Peptidyl-prolyl cis-trans isomerase D.
Peptidyl-prolyl cis-trans isomerase D (PPID)
PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and might thus assist protein folding (PubMed:11350175, PubMed:20676357). Proposed to function as a co-chaperone in HSP90 complexes such as in unligated steroid receptors heterocomplexes.
Different co- chaperones seem to compete for association with HSP90 thus establishing distinct HSP90-co-chaperone-receptor complexes with the capability to exert tissue-specific receptor action control. May have a preference for nitric oxide complexes and isn't found in glucocorticoid receptor complexes.
Gene Information
| Human | |
|---|---|
| Gene Name: | PPID |
| Uniprot: | Q08752 |
| Entrez: | 5481 |
Family
| Belongs to: |
|---|
| cyclophilin-type PPIase family |
Alternative Names
40 kDa peptidyl-prolyl cis-trans isomerase D; 40 kDa peptidyl-prolyl cis-trans isomerase; cyclophilin D; cyclophilin-40; Cyclophilin-related protein; CYP40; CYP-40cyclophilin 40; CYPD; EC 5.2.1.8; MGC33096; peptidyl-prolyl cis-trans isomerase D; peptidylprolyl isomerase D (cyclophilin D); peptidylprolyl isomerase D; PPIase D; Rotamase D
Molecular Weight
Mass (kDA):
40.764 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 4q32.1 |
| Sequence: | 4; NC_000004.12 (158709127..158723396, complement) |
Tissue Specificity
Widely expressed.
Subcellular Localizations
Cytoplasm. Nucleus, nucleolus. Nucleus, nucleoplasm.
Diseases
- Pituitary Diseases
- Horse Diseases
- Pituitary-dependent Cushing's Disease
- Malignant Neoplasms
- Nerve Degeneration
- Hyperplasia
- Neoplasms
- Cushing Syndrome
- Alzheimer's Disease
- Pain
- Edema
- Pain, Postoperative
Interacting Proteins
- APP
- ATP5PO
- ILF2
- RACK1
- RPS3
- XRCC6
Pathways
- Cell Death
- Pathogenesis
- Protein Folding
- Transport
- Necrotic Cell Death
- Transposition
- Cell Proliferation
- Circadian Rhythm
- Gene Silencing
- Cellular Homeostasis
- Mitochondrial Outer Membrane Permeabilization
- Aging
- Proteolysis
PTMs
- Nitration
Research Areas
- Immunology
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PPID
bosterbio.com/bosterbio-gene-info-cards/PPID
References
PMID: 8509368 by Kieffer L.J., et al. Cyclophilin-40, a protein with homology to the P59 component of the steroid receptor complex. Cloning of the cDNA and further characterization.
PMID: 8812478 by Yokoi H., et al. The structure and complete nucleotide sequence of the human cyclophilin 40 (PPID) gene.