PGRN Progranulin Human Recombinant Protein

GRN protein, Human

Progranulin Human Recombinant produced in HEK is a single, glycosylated, polypeptide chain containing 1-593 amino acids and having a molecular mass of 74kDa. The Progranulin is purified by standard chromatographic techniques.

Product Info Summary

SKU: PROTP28799
Size: 2ug, 10ug, 100ug
Origin Species: Human
Source: HEK293

Product Name

PGRN Progranulin Human Recombinant Protein

View all GRN recombinant proteins

SKU/Catalog Number

PROTP28799

Size

2ug, 10ug, 100ug

Description

Progranulin Human Recombinant produced in HEK is a single, glycosylated, polypeptide chain containing 1-593 amino acids and having a molecular mass of 74kDa. The Progranulin is purified by standard chromatographic techniques.

Storage & Handling

Lyophilized Progranulin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution PGRN should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

Cite This Product

PGRN Progranulin Human Recombinant Protein (Boster Biological Technology, Pleasanton CA, USA, Catalog # PROTP28799)

Form

Sterile Filtered White lyophilized (freeze-dried) powder.

Formulation

The protein contains 1xPBS.

Purity

Greater than 98.0% as determined by SDS-PAGE.

Predicted MW

63.544kDa

Reconstitution

It is recommended to reconstitute the lyophilized Progranulin in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Biological Activity

Activates phospho-ERK1/2 in neuronal mouse P19 cells and regulates food intake and body weight.

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Reconstitution

It is recommended to reconstitute the lyophilized Progranulin in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Validation Images & Assay Conditions

Gene/Protein Information For GRN (Source: Uniprot.org, NCBI)

Gene Name

GRN

Full Name

Progranulin

Weight

63.544kDa

Superfamily

granulin family

Alternative Names

Acrogranin; CLN11; GEP; GP88; granulin precursor; GRN; PCDGF; PEPI; PGRN; Proepithelin; Progranulin GRN CLN11, GEP, GP88, PCDGF, PEPI, PGRN granulin precursor progranulin|PC cell-derived growth factor|acrogranin|epithelin|glycoprotein 88|glycoprotein of 88 Kda|granulin-epithelin|granulins|proepithelin

*If product is indicated to react with multiple species, protein information is based on the gene entry specified above in "Species".

For more info on GRN, check out the GRN Infographic

GRN infographic

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In this infographic, you will see the following information for GRN: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact us at [email protected].

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Total: $300

SKU:PROTP28799

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