Product Info Summary
SKU: | A09335 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | ELISA, WB |
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Product info
Product Name
Anti-AAA1 SLC7A10 Antibody
SKU/Catalog Number
A09335
Size
100ul
Form
Liquid
Description
Boster Bio Anti-AAA1 SLC7A10 Antibody catalog # A09335. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-AAA1 SLC7A10 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A09335)
Host
Rabbit
Contents
Liquid form in PBS containing 50% glycerol,and 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human AAA1 protein.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A09335 is reactive to Slc7a10 in Human, Mouse, Rat
Applications
A09335 is guaranteed for ELISA, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
57.549kDa
Background of Slc7a10
Poly(A) polymerase that creates the 3'-poly(A) tail of specific pre-mRNAs. Localizes to nuclear speckles together with PIP5K1A and mediates polyadenylation of a select set of mRNAs, such as HMOX1. In addition to polyadenylation, it is also required for the 3'-end cleavage of pre-mRNAs: binds to the 3'UTR of targeted pre-mRNAs and promotes the recruitment and assembly of the CPSF complex on the 3'UTR of pre-mRNAs. In addition to adenylyltransferase activity, also has uridylyltransferase activity. However, the ATP ratio is higher than UTP in cells, suggesting that it functions primarily as a poly(A) polymerase. Acts as a specific terminal uridylyltransferase for U6 snRNA in vitro: responsible for a controlled elongation reaction that results in the restoration of the four 3'-terminal UMP-residues found in newly transcribed U6 snRNA. Not involved in replication-dependent histone mRNA degradation.
Ota T., Nat. Genet. 36:40-45(2004).
The MGC Project Team, Genome Res. 14:2121-2127(2004).
Trippe R.,RNA 12:1494-1504(2006).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB 1:500-2000 ELISA 1:5000-20000
Validation Images & Assay Conditions
There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.
Protein Target Info & Infographic
Gene/Protein Information For Slc7a10 (Source: Uniprot.org, NCBI)
Gene Name
Slc7a10
Full Name
Asc-type amino acid transporter 1
Weight
57.549kDa
Superfamily
amino acid-polyamine-organocation (APC) superfamily
Alternative Names
ASC1; asc-1; asc-type amino acid transporter 1; FLJ20839; HASC-1; solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10; solute carrier family 7 member 10; solute carrier family 7, (cationic amino acid transporter, y+ system) member 10; solute carrier family 7, (neutral amino acid transporter, y+ system) member 10 Slc7a10|AL024237, Asc, Asc-1, D7Bwg0847e|solute carrier family 7 (cationic amino acid transporter, y+ system), member 10|asc-type amino acid transporter 1|D-serine transporter|solute carrier family 7 member 10
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on Slc7a10, check out the Slc7a10 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for Slc7a10: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-AAA1 SLC7A10 Antibody (A09335)
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No publications found for A09335
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