Anti-ABCA4 Antibody Picoband™

ABCA4 antibody

Boster Bio Anti-ABCA4 Antibody Picoband™ catalog # A01048. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Product Info Summary

SKU: A01048
Size: 100 μg/vial
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: WB

Product Name

Anti-ABCA4 Antibody Picoband™

View all ABCA4 Antibodies

SKU/Catalog Number

A01048

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-ABCA4 Antibody Picoband™ catalog # A01048. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-ABCA4 Antibody Picoband™ (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01048)

Host

Rabbit

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human ABCA4, different from the related mouse sequence by eight amino acids.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins.

Reactive Species

A01048 is reactive to ABCA4 in Human, Mouse, Rat

Applications

A01048 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

256-300 kDa

Calculated molecular weight

255.944kDa

Background of ABCA4

ABCA4 (ATP-Binding Cassette, Subfamily A, Member 4), also known as ABCR, is a protein which in humans is encoded by the ABCA4 gene. ABCA4 is a member of the ATP-binding cassette transporter gene sub-family A (ABC1) found exclusively in multicellular eukaryotes. Using a whole genome radiation hybrid panel, this gene is mapped to 1p21-p13. And this gene is expressed exclusively in retina photoreceptor cells, indicating the gene product mediates transport of an essental molecule across the photoreceptor cell membrane. Additionally, it is showed by immunofluorescence microscopy and Western blot analysis that ABCR is present in foveal and peripheral cone, as well as rod, photoreceptors. The results suggested that the loss in central vision experienced by patients with Stargardt macular dystrophy arises directly from ABCR-mediated foveal cone degeneration.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml, Human, Mouse, Rat

Validation Images & Assay Conditions

Gene/Protein Information For ABCA4 (Source: Uniprot.org, NCBI)

Gene Name

ABCA4

Full Name

Retinal-specific phospholipid-transporting ATPase ABCA4

Weight

255.944kDa

Superfamily

ABC transporter superfamily

Alternative Names

ABC10; ABCRRMP; ARMD2DKFZp781N1972; ATP binding cassette transporter; ATP-binding cassette sub-family A member 4; ATP-binding cassette transporter, retinal-specific; ATP-binding cassette, sub-family A (ABC1), member 4; ATP-binding transporter, retina-specific; CORD3; EC 3.6.3; FFMFLJ17534; photoreceptor rim protein; retinal-specific ATP-binding cassette transporter; retina-specific ABC transporter; RIM ABC transporter; RIM protein; RmP; RP19; Stargardt disease protein; STGD; STGD1 ABCA4 ABC10, ABCR, ARMD2, CORD3, FFM, RMP, RP19, STGD, STGD1 ATP binding cassette subfamily A member 4 retinal-specific phospholipid-transporting ATPase ABCA4|ATP binding cassette transporter|ATP-binding cassette sub-family A member 4|ATP-binding cassette transporter, retinal-specific|ATP-binding cassette, sub-family A (ABC1), member 4|ATP-binding transporter, retina-specific|RIM ABC transporter|RIM protein|photoreceptor rim protein|retina-specific ABC transporter|retinal-specific ATP-binding cassette transporter|stargardt disease protein

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on ABCA4, check out the ABCA4 Infographic

ABCA4 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for ABCA4: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Size

Conjugation

Total: $370

SKU:A01048

In stock, 1 left.

Order within 31 hours and 34 minutes to receive by Thu Mar 21

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A01048
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00

$50 fee for conjugation. Antibody size is reduced to 50ug.

Troubleshooting

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